Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

PHARM 443 : Sex Ed/MSK > Lecture 5 > Flashcards

Lecture 5 Flashcards

1
Q

What are examples of progestin only pills ?

A

Norethindrone
Drospirenome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

When can a patient use a POP ?

A

Avoid estrogen ( migraines with aura, smoking >35 yo)

Postpartum and breastfeeding

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are the contraindications for progestin-only medications?

A

breast cancers, history of cancer, liver diseases and inducers ( CYP3A4: anticonvulsants and rifampin)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are the main counselling point when a pt will take norethindrone ?

A

TIMING!
Missed dose ( not more than 3 hours)
Take it ALL the TIME ( no break)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is the MOA of norethindrone

A

Progestin analog
Cervical mucus more thick and can stop ovulation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Which contraceptive helps with acne tx ?

A

Drospirenone with the anti-antiandrogenic abilities

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is the MOA of drospirenone ?

A

Progestin ONLY
Inhibits ovulation + thick mucus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

If a pt starts drospironone outside of 1st day of menses , what would you counsel ?

A

recommend a 7 days backup

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Why is there a longer back up time with drospirenone compared to norethindrone ?

A

Drospirenone has a longer 1/2 life than norethindrone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Which POP has hyperkalemia SE ?

A

Drospirenone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are the common progestin SE ?

A

Mood, headache, breast tenderness,

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Who would best benefit from DMPA ?

A

pts that are on anticonvulsant , no exposure to estrogen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

How frequent does a pt is injected for DMPA ?

A

every 3 months (in week 12-13)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What would you counsel a pt that is starting DMPA on day 10 of cycle ?

A

requires 7 days back up

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is a major SE from DMPA to mention to pt ?

A

weight gain , delay in fertility ( 9 months)

others : progestin SE ( mood, headache, breast tenderness) , menstrual cycle disturbance

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

When would you need backup for DMPA ?

A

missed dose after 14 weeks
starting after 5 days of normal cycle

7 days back up

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

When is the safe age gap for DMPA in terms of loss of bone mineral density ?

A

18 - 45 years old

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What is the MOA of LNG IUS ?

A

LNG releasing system
Thinning of uterus lining
Stops sperm
Thick mucus

19
Q

What are the additional indications of LNG IUS ?

A

Dysmenorrhea
Heavy and abnormal bleeding
Protects from estrogens ( endometrial protection)

20
Q

What is the main difference between the Mirena and kylena ?

A

both LNG IUS
Kyleena releases less LNG doses

Mirena –> “more”

21
Q

What is the bleeding events - menstrual with patients on LNG IUS ?

A

reduced mens
amenorrhea is also common

22
Q

What are the SE of LNG IUS ?

A

irregular bleeding
Pain at insertion
Systemic LNG levels ( less than CHC) = mood, breast tenderness, headache

23
Q

What are the contraindications for intrauterine contraceptions ?

A

Pregnancy
Current PID
Current breast cancer
Undiagnosed abnormal uterine bleeding
Previous risk of breast cancer
Postpartum > 48 hours to 4 weeks

24
Q

What is the MOA of copper IUD ?

A

Copper ions inhibits sperm movement

25
Q

What are the SE of copper IUD ?

A

irregular bleeding/ BTB ( more than LNG IUS)
more dysmenorrhea, pelvic pain, cramps than LNG IUS

26
Q

Do you need backup with copper IUD ?

A

No it works right away

27
Q

what are the risks of IUD ?

A

Expulsion (first ear, heacy mens,. Atypical anatomy )
Perforation
PID
Vasovagal reaction /fainting with insertion

28
Q

What is within a contraceptive implant ?

A

Progestin subdermal
Etonogestrel - 3rd gen

29
Q

How long can one keep the contraceptive implant inside ? m

A

for 3 years

30
Q

What is the MAIN MOA of contraceptive implant ?

A

STOPS OVULATION
thicken mucus and atrophic endo

31
Q

What happens to the fertility of contraceptive implants ?

A

Fertility returns in ONE month after removal

32
Q

What are the SE of contraceptive implants ?

A

Irregular bleeding or breakthrough bleeding
Progestin related
Weight Gain

33
Q

What should we do moving from CHC oral patch/ ring to LARC ?

A

CHC for 7 days after insertion

34
Q

What should we do DMPA to LARC?

A

No later than 13 weeks after the last injection

35
Q

What can be said about transgender with ova and uterus ?

A

With ova + uterus → ovarian function is not fully suppressed while on testosterone
Needs : NO estrogen → POP, IUD,n copper IUD

36
Q

If a patient is on anticonvulsants what contraceptive would you recommend ?

A

Try IUD
if CHC ( minimum 30-35 ug of EE) , longer ½ lfe progestin ( 2nd gen)
Continuous/ external interval dosing + backup

37
Q

What is the recommendations fo pts with migraines + AURA ?

A

Contraindications!
More risk of ischemic stroke
NO CHC , avoid estrogen

38
Q

What is the recommendations for pts with MIGRAINE ?

A

Are they linked to hormones ? continuous or HFI
Continue with CHC or estrogen in HFI
Recommend if worse care : POP, IUD, implant.

39
Q

What are the recommendations for obese pts ?

A

Assumed lower efficacy in patches, COC → Increase the risk of VTE with more weight
Recommend : IUD ( even with LNG )

40
Q

When can a breastfeeding mom potentially use CHC or POP ?

A

Decrease breastfeeding → ovulation can start
< 6weeks : avoid CHC only POP , estrogen → affects prolactin
> 6 weeks : preference of POP&raquo_space; CHC

41
Q

What does WHO say for non breastfeeding mom ?

A

WHO : <3 weeks + Not Breastfeeding → avoid CHC, hypercoagulale state
Wait 6 weeks if VTE risk !!

42
Q

When is the ideal time to use IUD postpartum ?

A

< 48 hours ideal but HIGHER rates of expulsion
> 48 hours → wait 4 weeks

43
Q

When can contraceptives be used by postpartum women ?

A

> 4 weeks

44
Q

What are the SE of copper IUD ?

A

More Irregular bleeding or breakthrough bleeding
More risks of dysmenorrhea, pelvic pain, cramps
Pain at placement

PHARM 443 : Sex Ed/MSK (10 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions