Lecture 6

Question 1

What was the first drug used to treat schizophrenia?

Answer 1

Chlorpromazine

Question 2

What are typical antiphyscotics ) what are problems with their use?

Answer 2

Typical anti phycotis are dopamine receptor antagonists (d2), good at treating positive symptoms, poor at treating negative symptoms and cognitive also nos sever side motor effects

Question 3

What pathway is associated with the positive symptoms of schiphina

Answer 3

The mesolimbic (subcortical) pathway

Question 4

What pathway is associated with and the negative cognitive symptoms of shizephenia

Answer 4

Meso cortical pathway

Question 5

Why do patents treated with antiphycotis snow motor side effects?

Answer 5

Decreased dopamine intopathway ligrastriatal (extrapirimidal)

Question 6

What is a atipal antiphycotic

Answer 6

Antiphycot: c but with reduced extrapyrimidal side effectsand more effective against negative and cognitive symptoms and also fact on many diffract rector subtypes

Question 7

what is the difference between a typical and atypical antiphycotic?

Answer 7

typical - just dopamine
atypical also 5-HT