Lecture 5 Regulation of Respiration Flashcards
what controls RR to meet the need for o2 to the body?
Medulla
What is the dorsal respiratory group mainly responsible for?
Inspiration and sensory information
what peripheral receptors does the dorsal respiratory group sense specifically?
Chemoreceptors
Baroreceptors
Lung Receptors (distention and filling)
the dorsal group fires of two sequential actions in respiratoin?
- inspiration
2. inhibition of inspiration
although the dorsal group regulates respiration in “ramping” up slowly, and expiring quickly all under 2 seconds, what else assists in that process?
The pneumotaxic center
What does the pneumotaxic center mainly control
rate and pattern of breathing
where is the pneumotaxic center located?
Dorsal pons
what is the MAIN goal of the pneumotaxic center?
To shorten inspiration, and thereby increasing the frequency
What is the name of the effect when the Pneumotaxic center senses lung stretch at 1.5 liters, abruptly ending inspiration?
Hering Breuer effect (prevents damage from overfilling)
What 3 substances in order of importance regulate breathing?
- Co2 (Hypercapnia is the biggie)
- H+ (less mobile than co2)
- Oxygen (very little contribution here)
Physiologically, will you generally see an accumulation of co2 before acidity increases, or acidity before co2 increases?
Co2 will accumulate first, which leads to production of acid (H+)
Although co2 is the main contributor of breathing, what is the STRONGEST contributor if it accumulates enough?
Hydrogen ions (H+) (Remember: renal system still does its job, but if H+ gets high to make an effect, its likely super high)
o2 as a regulator will not become functional until peripheral chemo receptors detect a drop below what value?
70mmhg po2
at what value will the low po2 causing a doubling of breathing?
60mmhg po2
in what environmental condition does o2 begin to play a more important role in breathing regulation?
low o2/high altitude situations
b/c you blew off all your co2 over compensating for low atmospheric o2
