Last quiz before final Flashcards
Why is the enteric system’s nervous system special?
Regulated intrinsically by sympathetic and parasympathetics
Do sym/parasym neurons go straight to the effector organ or synapse first in glanglions?
synapse in ganglions
Several different levels of CNS each sharing control over a single target organ is called a….
safety mechanism
What are the 4 Sympathetic receptor types….
a1,a2,b1,b2
What is the single Parasympathetic target receptor types…
Muscarinic
What is the single Somatic receptor types….
Nicotinic
But both sympathetic and parasympathetic give off what pre-synaptic neurotransmitter to what receptor type ALWAYS
Acetylcholine at Nicotinic receptor sites.
At the effector organ, what NT’s synapse w/ the sympathetic (alpha1/2, beta1/2) receptors?
Catecholamines (epi,norepi,dopa)
At the effector organ, what NT synapses w/ the parasympathetic Muscarinic receptors?
Acetylcholine
Neural crest cells (AKA Chromaffin cells) form to become what thing in the adrenals?
They become the adrenal medulla
that secrete 20% epi, 80% norepi
Alpha 1 cells are__________, while Alpha 2 cells are__________?
(options: inhibitory/ excitatory)
Excitatory, Inhibitory
Vasculature, Iris muscles, the bladder sphincter,
the GI tract, and smooth muscles in the skin
are alpha 1 or alpha 2 receptored??
Alpha 1
Platelets, adipocytes, GI tract are alpha 1 or alpha 2?
Alpha 2
SA node, AV node, ventricular muscles are Beta 1 or beta 2?B
Beta 1
Vasculature supplying skeletal muscles, bronchial walls, GI tract, bladder wall are beta 1 or beta 2?
Beta 2
Every receptor throughout the body in any system generally activates or inhibits cAMP, what is the only one receptor type that then works on IP3-CA2+?
Alpha 1 receptors
Are receptors more sensetive to epi or norepi?
epi
We know that sympathetics increase HR activity, constrict GI, decrease GI motility, dilate skeletal peripheral vessels, dilate bronchioles, relax the bladder wall, cause ejaculation, and increase sweating…which one of these is ALSO done in parasympathetic action?
Increased sweating (otherwise, parasympathetics do the opposite of all those)
TRUE or FALSE, parasympathetics have the ability to alter vascular smooth muscle
FALSE! (mediated by sympathetics only!)
she hinted at this as a quiz question
TRUE or FALSE, parasympathetics can alter renin section and/or lipolysis of fat cells?
FALSE!
Vibrations, Skin movement, Joint position, and Fine tuned pressure/touch sensation and localization comes from what afferent system?
Dorsal column system
aka Medial Lemniscus pathway
Pain, Hot/Cold, Crude touch and pressure sensation/localization, tickle/itch, and sexual sensations are all part of what afferent system?
Anterolateral System
Therefore, both Dorsal and Anterolateral tracts of the spinal cord are part of what pathway?
Sensory / Ascending / Afferent
The anterolateral tract only goes _______ the speed of the dorsal column?
a) 1/3 b) 1/5 c) same speed
a) 1/3rd
What explains the “crude” sensation of the anterolateral system?
it only has 10-20 gradations of sensetivity
How many gradations of sensetivity does the dorsal column (fine tune sensory) have?
100
You feel a vibration and it goes to the dorsal root of the your spinal cord where it splits into what two areas at the same level?
Medial (where it then goes up to the brain)
Lateral (goes into the grey matter for spinal reflex)
Are sensory fibers delivering this good vibration to the brain via large myelinated fibers or small -non-myelinated fibers?
Large myelinated fibers
First order neurons (that good vibration now ascending the dorsal column) enters what area of the CNS?
The Dorsal Medulla/Dorsal Nuclei
Second order neurons (in theory) cross over to the opposite side of the body (decussate) and ultimately end up where?
In the thalamus (thalamic sensory relay)
Third order neurons project their fibers into what?
The post-central gyrus (AKA the Homonculus)
That place in the brain where the body is stretched out over it like a sensory road map, with the big face and mouth.
The anterolateral system (carrying Temp, tickle, pain, sex) the sensory fibers always terminate where?
They terminate in the dorsal root
Once anterolateral fibers terminate in the root, they immediately synapse with a new fiber that….
a) stays on the same side and goes up
b) immediately crosses over and goes up
b) Immediately crosses over and ascends
Pain fibers from the anterolateral system enter the….
Reticular nucleus of the brainstem
Review:
without the dorsal column, if we close our eyes can we still maintain position and prioception?
No
but we can still feel pain, tickle, sex, etc
Review:
Without the anterolateral system, what can and can’t we do?
We cant feel pain/itch/hot/cold/tickle/sex
but we can still sense position and proprioception.
What is the mnemonic sentence for what the Anterolateral system controls?
Ive got a PAINFUL ITCH for HOT TICKLE SEX
hot includes hot/cold sensing
In the sensory area of the brain called the post-central gyrus, what two areas of the body take the highest priority?
The face (lips especially) and hands
Skin, viscera, muscles, and periosteum have what type of nerve endings (myelinated or unmyelinated)
unmyelinated free nerve endings
What is the NT of choice for pain communication?
Substance P
What blocks/inhibits substance P
Opioids
Fast pain fibers (group III) are fast on/fast off and are_________
a) well localized
b) poorly localized
well localized
Slow pain fibers (Group IV) are carried by C fibers and sense what perceptions?
aching, burning, throbbing that is difficult to localize
This type of pain (nociception) is felt in the area that is innervated by nerves from the SAME SPINAL CORD segment
Referred pain
all visceral pain is technically referred pain
All muscle fibers innervated by a single motor neuron is called a….
motor unit
the set of all motor neurons that innervate fibers within the same muscle
Motor neuron pool
The force of a muscle contraction is graded by the additional motor units from a pool….true or false?
TRUE
Muscle spindle fibers (group 1a & 2) detect…
static (1a) and dynamic changes (2) in muscle length
Golgi tendon organ fibers (1b fibers) detect…
muscle tension
Pacinian Corpuscule fibers (II fibers) detect…
Pain (they use substance P as their NT)