lecture 5

Question 1

What is the overall reaction for B - oxidation of fatty acids?

Answer 1

Cn-ACYL-CoA + FAD + NAD+ + H2O + CoA

goes to Cn-2-ACYL-CoA + FADH2 + NADH + H+ + ACETYL-CoA

Question 2

What is the example equation for Palmitoyl - CoA

Answer 2

Palmitoyl-CoA + 7 FAD + 7 NAD+ + 7 H2O + 7 CoA

goes to 8 acetyl-CoA + 7 FADH2 + 7 NADH + 7H+

Question 3

What happens to the acetyl -CoA produced?

Answer 3

• enters the citric acid cycle

- made into ketone bodies

Question 4

What is the overall ATP produced from palmitoyl coA production and going through TCA cycle?

Answer 4

130 But - 2 therefore 129

Question 5

Which produce more energy : fats or carbohydrates?

Answer 5

• fats - 8.2

- carbs - 6.3

Question 6

What is Ketogenesis?

Answer 6

• Acetyl -CoA converted into acetoacetate and D-B-hydroxybutyrane

Question 7

where does Ketogenesis occur?

Answer 7

• occurs primarily in the mitochondria in the liver

Question 8

What are the ketones bodies?

Answer 8

acetoacetate + D-3-hyrdoxybutyrate

Question 9

Why are ketone bodies primarily found in the liver?

Answer 9

• Where most of the oxaloacetate is used for gluconeogenesis
• oxaloacetate is needed for the TCA to work

Question 10

When do we mainly use ketone bodies?

Answer 10

when we are fasting/don’t have enough carbohydrates

Question 11

What can ketone bodies be described as?

Answer 11

• water soluble equivalents of fatty acids

- ‘energy rich’

Question 12

What are the major uses of ketone bodies?

Answer 12

• heart and renal cortex

Question 13

What do you have to do you silly bitch?

Answer 13

• look at my notes and learn all the enzyme shit