Lecture 45: Cholesterol Transport and Uptake Flashcards
What are lipoprotein particles?
They are spherical particles with varying amounts of lipid and protein.
The maintain the solubility of lipids and transport them in the plasma.
What are the lipid components of lipoprotein particles?
triacylglycerol
cholesterol esters
phospholipids
What are the protein components of lipoprotein particles?
apolipoproteins (A-E)
What is the importance of lipoprotein particles?
important in release of lipoprotein particles from the cell
mediate uptake of lipoprotein particles into cells
activate lipid processing enzymes
What percentage of chylomicrons are triacylglycerol?
90%
Which lipoprotein particle has the least density?
HDL
What is the name of the disease that is linked to elevated plasma and/or chylomicrons which cause small pustules in the skin?
Cutaneous xanthomas
T/F: Tuberous xanthomas are harder and more firm and thicker than cutaneous xanthomas.
True.
Where are chylomicrons assembled?
intestine
What is a specific distinguishing marker for chylomicrons
apo B48
Where are VLDL and LDL made?
They are made in the liver
What is the distinguishing marker of VLDL and LDL?
apo B 100
