Lecture 4 -Protein Synthesis, structure, function, & degradation Flashcards
Proetin synthesis is the ___ consumer of energy during proliferation
largest
In cellular partitioning, translation is…
cytoplasmic
Does translation happen in or outside of the nucleus?
outside
How do you tell if the RNA is mRNA?
from the 5’ cap and the 3’ PolyA tail
the 5’___ and the 3’___ is required to _____
Cap, PolyA tail….. by protein synthesis machinery to start translation
Define cytoplasmic translation
process where sequence of nucleotides in a mRNA directs the incorporation of amino acids into proteins
the mRNA harbors the _____
genetic code (rules by which the nucleotide seq. of a gene is translated into amino acid seq.)
what does it mean to say that the codon code is redundant and degenerate?
that there are many amino acids for more than 1 codon
how many stop codons are there?
3
what are anticodons?
3 nucleotides that pair with the complementary codon in an mRNA molecule
Codons are matched w/ their amino acid via molecular adaptors, _______
Transfer RNAs (tRNAs)
primary sequence is a _____, 2nd sequence is _____, and 3rd sequence is ____
string, cloverleaf, and many foldings
what are tRNAs?
transfer RNAs
specific enzymes _______ couple tRNAs to the correct amino acids
aminoacyl-tRNA synthetases
what is CMT disease?
Charcot-Marie-Tooth, which affects sensory and motor neurons degeneration, is linked to 6 mutations
