Lecture 4 practise questions Flashcards
1
Q
What is the protective role of the healthy endothelium against plaque formation in arteries?
A
a
2
Q
Define M-CSF and outline its role in the development of atherosclerotic plaque.
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a
3
Q
What is the role of TNFa and VCAM-1?
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a
4
Q
What is a key player in the breakdown of the fibrous cap and subsequent thrombus release? Describe.
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a
5
Q
How does the CANTOS study (Ridker, 2017) support the ‘inflammatory hypothesis’ of heart disease?
A
a
6
Q
What does ventilation-perfusion mismatching represent in patients with heart failure - include the physiological
mechanism and the key symptom?
A
a
