Lecture 4: IV administration Flashcards

1
Q

Why can’t all IV medications be given rapidly?

A

Infusion-related reactions and complications may result

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2
Q

What should be considered to determine which type of IV administration to be used? (Push/Intermittent/Continuous)

A

medication
concentration
total volume

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3
Q

Compounding IV push/IV intermittent

A

Reconstitution/further dilution
Stock solution
Sometimes no compounding is necessary
- straight draw out of vial, no dilution or manipulation needed

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4
Q

IV administration

A

can be central or peripheral

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5
Q

Vascular access device (VAD)

A

term that encompasses both peripheral and central access

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6
Q

Peripheral catheter

A

small IV catheter placed into small peripheral vein for short-term use

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7
Q

Central venous catheter (CVC)

A

IV catheter terminating at superior vena cava

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8
Q

Catheters used for medication, fluids, TPN, and blood draws

A

Peripheral catheter
Central venous catheter

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9
Q

Types of central venous catheters

A

Peripherally inserted central catheter (PICC)
Long term central catheter (LTCC)

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10
Q

Peripherally inserted central catheter (PICC)

A

Inserted at peripheral site
travels into superior vena cava

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11
Q

Long term central catheter (LTCC)

A

mediport
tunneled CVC

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12
Q

Benefits of peripheral catheter

A

Convenient easy to use
minimal ADR

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13
Q

Risks of peripheral catheters

A

Limitations of what can be infused
short term use hrs-days

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14
Q

Benefits of central catheters

A

Fever limitations on what can be infused
Long term use wks/mon/yrs

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15
Q

Cons of central catheters

A

Placement requires trained personnel, may require sedation
Complications
- infection of central line
- line fracture/break

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16
Q

Phlebitis

A

Inflammation of the vein

17
Q

How does phlebitis occur?

A

at placement of vascular access device (VAD) and in the direction of blood flow

18
Q

Phlebitis is characterized by

A

Tenderness
Redness
Puffiness
Increased temperature

19
Q

IV infiltration

A

Fluid/medication infuses into the tissues surrounding the venipuncture site

20
Q

IV infiltration occurs when

A

Tip of the catheter slips out of the vein
Catheter passes through the wall of the vein
Blood vessel wall allows part of the fluid/medication to infuse into the surrounding tissue

21
Q

Signs and symptoms of IV inflitration

A

Redness around the site
Swelling, puffy or hard skin
Pain
Blanching
IV not working
Cool skin temperature around the IV site or the scalp, hand, arm, leg or foot near the site

22
Q

Vesicant

A

drug that results in tissue necrosis when accidentally infused into the tissues surrounding a vein

23
Q

Examples of vesicants

A

Neurotransmitters (NE,DA, EPI)
Chemotherapies
calcium salts

24
Q

Extravasation

A

Infiltration of a vesicant into the surrounding tissue

25
Q

Signs/symptoms of extravasation

A

Pain, stinging/burning, edema
Can result in tissue necrosis
Can progress to permanent tissue damage requiring surgery or amputation

26
Q

Management of extravasation

A
  1. Stop IV fluid administration
  2. Disconnect IV tubing from cannula at the vascular access device
  3. Aspirate any residual drug from the cannula
  4. Administer a drug-specific antidote as indicated
  5. Elevate limb with extravasation
  6. Local cooling or warming to site as indicated (drug specific)
27
Q

Assessing for compatibility

A

Y site
Admixture
Syringe

28
Q

Incompatibility

A

when a combination of medications and or fluids results in a product unsuitable for administration to the patient

29
Q

Physical incompatibility

A

Change in color
Formation of turbidity
Precipitation
Evolution of a gas

30
Q

Chemical incompatibility

A

results in degradation of drug substance
≥ 10% loss of intact drug within 24 hours

31
Q

Factors for determining compatibility

A

pH is the primary factor
Salt form matters (succinate vs phosphate)
Formulation matters (liposomal vs deoxycholate)

32
Q

CSP stability

A

extent to which medication preparation remains within specified limits in terms of
1. Chemical composition
2. Physical composition
3. Microbiologic activity/contamination
Subject to specific storage conditions
- CRT, Refrigerator, Freezer
Take BUD into consideration

33
Q

Assigning BUD

A

never longer than manufacturer’s exp
Shortest BUD based on sterility AND stability

34
Q

Reference for IV compatibility

A

Trissel’s