Lecture 4- Diencephalon Flashcards

1
Q

External features of diencephalon

A
Optic chiasm
Mamillary bodies
Lateral geniculate bodies
Medial geniculate bodies
Tuber cinereum
Infundibulum (pituitary stalk)
Cerebral peduncle
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2
Q

Surfaces of diencephalon

A
Medial: 3rd ventricle with interthalamic adhesion
Dorsal: Fornix
Lateral: Internal capsule
Ventral: front- optic chiasm
              sides- optic tracts
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3
Q

Subdivisions of diencephalon

A

Thalamus
Epithalamus
Subthalamus
Hypothalamus

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4
Q

Functional classification of thalamus

A

Specific nuclei
Association/relay nuclei
Non-specific nuclei

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5
Q

Structural classification of thalamus

A

Divided into 3 cell groups by y-shaped internal medullary lamina
Anterior
Lateral:
Dorsal- lateral dorsal, lateral posterior, pulvinar
Ventral- ventral anterior, Ventral lateral, ventral
posterior
Medial
Others

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6
Q

Specific nuclei and examples

A
Have a reciprocal connection to specific motor or sensory areas of cerebral cortex
Ventral anterior nucleus
Ventral lateral nucleus
Ventral posterior nucleus
Metathalamus
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7
Q

Ventral anterior nucleus goes to

A

Prefrontal cortex (motor)

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8
Q

Ventral lateral nucleus goes to

A

Posterior portion goes to primary motor area

Anterior portion goes to secondary motor area

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9
Q

Ventral posterior nucleus goes to

A

Somatosensory area
Sensations from the skin, muscles and internal viscera
ONLY the consciously perceived parts
Special senses of position awareness, movements and taste

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10
Q

Metathalamus

A

Medial geniculate nuclei: primary auditory cortical areas

Lateral geniculate nulcei: Primary visual cortical area

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11
Q

Association nuclei and examples

A

Reciprocally connected to association areas of cerebral cortex
Anterior nucleus
Mediodorsal nucleus
Pulvinar

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12
Q

Anterior nucleus goes to

A
Limbic system (cingulate gyrus)
Memory and behavioural functions
(reproductive and defense)
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13
Q

Mediodorsal nucleus goes to

A

Limbic system and frontal lobe

Cognition (thinking) and judgement

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14
Q

Pulvinar goes to

A

Nuclear complex

Function not well understood but connects to parietal, temporal and occipital cortices

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15
Q

Non-Specific nuclei and examples

A

Involved in different levels of consciousness and degree of alertness
Reticular nucleus
Intralaminar nucleus

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16
Q

Epithalamus consists of

A
Habenular nucleus
Habenular commissure
Striae medullaris
Epiphysis (pineal gland)
Posterior commissure
17
Q

Habenular nucleus

A

Slight swelling in the habenular trigone medial to posterior surface of thalamus
Integration of olfactory, visceral and somatic pathways and sleep mechanisms
Link the limbic system to the brainstem via afferent fibres that pass through striae medullaris thalami

18
Q

Habenular commissure

A

Formed by lateral striae medullaris that cross the midline and reach habenular nucleus of opposite side

19
Q

Pineal gland

A

Small, reddish conical endocrine gland
Attached to diencephalon by pineal stalk
Calcification results in brain sands (corpora arenacae @ 30 years old)
Usually lies slightly to the left

20
Q

2 cell types of pineal gland

A

Principal pinealocytes: synthesize melatonin from serotonin; implicated in sleep-wake cycle (secreted mostly at night and inhibited in daytime)

Neuroglia: support cells

21
Q

Functional roles of Epithalamus

A
Regulation of cyclic behaviours
- circadian rhythm
- reproductive cycles
- day/night cycle
Modulation of other systems in the brain 
- limbic system
- hypothalamus
- raphe
- some motor-related pathways
22
Q

Subthalamus

A

Wedged between thalamus and hypothalamus
Consists of
- Subthalamic nuclei and zona incerta

23
Q

Ventral thalamic nucleus characteristics

A

Biconvex
Lies against internal capsule
5 distinct nuclei
Ventral to the dorsal thalamus and dorsal to the basis pedunculi/crus cerebri

24
Q

Nuclei of the ventral thalamus (subthalamus)

A
Subthalamic nucleus
Zona incerta
Nucleus of field H of Forel (subthalamic reticular nucleus)
Subthalamic reticular nucleus
Ventral lateral geniculate nucleus
Thalamic reticular nucleus
25
Subthalamic nucleus
Reciprocal connections with globus pallidus Serves as a relay from globus pallidus to substantia nigra and vice versa Projects upon the cordate-putamen
26
Zona incerta projections
Receives projections from - sensory and motor cortex - ventral lateral geniculate nucleus - trigeminal nucleus - cerebellar nuclei - spinal cord Projects to - pretectum - posterior lobe of epiphysis - spinal cord
27
Function of subthalamic fasciculus
Control of skeletal muscle activity | Lesion causes motor disturbances (hemiballismus, sudden, involuntary purposeless movement) on opposite side
28
Zona incerta
Rostral extension of reticular formation Lies between thalamus and subthalamic nucleus Associated with regulation of thirst
29
Hypothalamus and boundaries
``` Occupies a small amount of weight Superior: Hypothalamic sulcus Inferior: Optic chiasm, tuber cinereum, mamillary bodies Anterior: Lamina terminalis Posterior: Tegmentum of midbrain Medial: 3rd ventricle Lateral: Internal capsule ```
30
Hypothalamic nuclear groups
Anterior group Intermediate group Posterior group Mostly ill-defined boundaries
31
Functions of hypothalamus
``` Control of hypophysis (pituitary gland) Control of autonomic centres Temperature regulation Regulation of food and water intake Emotions and behaviour Control of circadian rhythms Memory ```
32
Hypothalamic control over autonomic centres
Anterior hypothalamic area for parasympathetic effects
33
Hypothalamic control over temp regulation
Ant area: Responds to increase in temp | Post area: Responds to decrease in temp