lecture 4- cell membranes Flashcards
cells need to … to survive
•grow •reproduce •respond to outside stimuli and movement
purpose of a membrane
to separate the cellular content from the environment
amphipathic
2 parts hydrophilic an polar glycerol head and hydrophobic and no polar fatty acid tail
non polar tails
long chain fatty acid attached to a polar head
how to increase membrane fluidity
increase unsaturated fatty acids - because the linkage isn’t as tightly packed •or increase the temp
glycerophospholipids
backbone glycerol-3- phosphate
fatty acyl group
combination of a carboxyl carbon and its hydrocarbon tail in a lipid
saturated
non double bonds •only single bond
phosphate group of phosphitidate
becomes esterified to the oh group
reminder
know how to draw glycerophospholipids
4 common glycerophospholipids
- phosphatidylcholine (lecithin) PC
- phosphatidyethanola-mine (PE)
- phosphatidyerie (PS)
- Phospatidylinositol (PI)
sphingolipids-
•2nd group of lipids in membranes backbone- sphingosine- a long chain alcohol •single lipid •amnesias group nh3+ •C1 hydroxyl group - attached to polar head
3 types of sphgolipids
- sphingomylins- contains phospate
2 and 3 cerobrosides and ganglioside - contains carbohydrate residue
cholesterol
•lipid that contains sugar •heart attacks or stroke
tay says disease
enzymes involved Hexosaminiidase A absent •ganglioside builds up in brain destroys nerves •red spot in retina - dead before 3 •unable to swallow, breath and paralysed