Lecture 4 Flashcards

1
Q

what is an Endomembrane system

A

a membrane system interconnected by direct physical contact or transfer by vesicles

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2
Q

what does the endomembrane system include

A

nuclear envelope, lysosomes, ER, vacuoles, golgi apparatus, plasma membrane and vesicles

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3
Q

What are the two types of Endoplasmic Reticulum

A

Smooth and Rough

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4
Q

What are the functions of sER

A

Metabolism of Carbohydrates
Lipid Synthesis/formation
Detox of Drugs/poison
Storage of calcium ions

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5
Q

how does sER meet the demand of its processes in cells

A

it can increase/decrease to meet demand

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6
Q

What is rER and what its functions

A

ER covered in ribosomes,

ribosomes for protein synthesis/production

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7
Q

what happens to rER proteins

A

secreted and membrane-bound proteins enter lumen(inferior) of rER
Processed for release from cell or retention on cell membrane

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8
Q

What is the Golgi Complex

A

series of membrane sacs and associated vesicles

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9
Q

What are the functions of the Golgi Complex

A

Receives,modifies, sorts and ships proteins arriving from rER

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10
Q

What are the cis and trans face of the Golgi complex

A

has polarity: cis and trans face
Vesicles from ER arrive at Cis face
Processed vesicles leave at trans face

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11
Q

what is Glycosytation

A

the addition or modification of carbohydrate sugar to proteins, this is important for secreted or cell surface proteins

can also produces polysaccharide-can be secreted from cell

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12
Q

how does the Golgi complex sort proteins

A

it adds markers to proteins to sort in correct vesicles leaving cell

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13
Q

how does the Golgi complex direct vesicle trafficking

A

it tags vesicles with short proteins to direct to the lysosome and secretory pathways

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14
Q

what is exocytosis

A

transport material/glycoproteins out of cell or to the cell surface

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15
Q

What is constitutive exocytosis

A

relatively unregulated- releases ECM proteins

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16
Q

what is regulated exocytosis

A

releases hormones and neurotransmitters

17
Q

What is endocytosis

A

process that takes in molecules/particles at plasma membrane

18
Q

what is Phagocytosis

A

when a cell is “eating” uptake of food particles

forms phagocytic vacuole (large vesicle), digested by lysosomes

19
Q

What is Pinocytosis

A

when a cell is “drinking”- extracellular fluid, containing solutes such as protein/sugars
coat proteins, helps with structure

20
Q

What is receptor-mediated endocytosis

A

specialized pinocytosis where receptors take up specific solutes that can take up low-concentration in bulk

21
Q

what are lysosomes

A

membrane-bound organelles made by rER and Golgi body, the interior is acidic/would kill cell but needed for enzyme activity

22
Q

what is the function of lysosomes

A

they degrade lipids, carbohydrates and nucleic acids- products into cell

23
Q

what is autophagy

A

digesting and recycling unwanted cellular material

24
Q

what are vacuoles

A

large vesicles dervied from rER and Golgi

food vacuoles-phagocytosis

25
Q

what are the functions of vacuoles

A

lysosomes functions
store organic compound (proteins,pigments)
absorb water for plant growth with increased cytoplasm