Lecture 35: Growth Hormone

Question 1

Hyposecretion of GH causes?

Answer 1

• Dwarfism - too little GH

Question 2

Hyper secretion of GH causes?

Answer 2

• Gigantism - too much GH

- Acromegally - too much in adults

Question 3

GH secretion in females is . . . ?

Answer 3

• more consistent
• sustained shallow peaks
• low level of GH compared to men

Question 4

GH secretion in males is . . . ?

Answer 4

• less consistent
• sharper less consistent peaks
• High level of GH compared to women

Question 5

What effect does GH have on the metabolism?

Answer 5

• increases BG by stimulating glucose synthesis
• decrease glucose uptake
• increases fat breakdown

Question 6

What effect does GH have on the liver?

Answer 6

• release of insulin-like-growth factor 1 from liver stimulates the growth of bone, muscles and tissues by stimulating cell division

Question 7

What effect does GH have on muscles?

Answer 7

• protein synthesis

- reduces glucose uptake

Question 8

What effect does GH have on adipose tissue?

Answer 8

• causes adipose tissue fat breakdown

- breakdown produces fatty acids which is then used for fuel

Question 9

What inhibits the release of GH?

Answer 9

Somatostatin - GHIH (growth hormone inhibiting hormone)

Question 10

What stimuli cause the release of GHRH from the hypothalamus?

Answer 10

• sleep
• excercise
• stress
• low blood glucose