Lecture 33 Flashcards
Alcohol and Exercise
in high quantities alcohol is toxic to what
liver and brain
alcohol acts as
depressant and a diuretic.
alcohol is ….
carcinogenic
alcohol can substantially increase ….
alcohol can substaintially increase energy intake
alcohol changes your what ratios and what can this have a small protective affect against
alcohol changes your cholesterol ratios
can be possible small protective effect against CHD if consumed in moderation
toxicity of liver and effects of kidney function outweigh
any positive effects
what are the effects of alcohol on catabolism
- free fatty acid mobilisation
- glucose uptake
what are the brain function effects of alcohol
- cognition
- motor control
what are the effects of alcohol on anabolism
- protein synthesis
- glycogenesis
how does alcohol effect immunity
- adaptive immunity
- innate immunity
how does alcohol affect fluid balance
- water balance
- electrolyte balance
how does alcohol affect thermoregulation
skin vasodilation
how does alcohol affect vascular haemodynamics
- blood pressure
- blood supply
what % of alcohol is excreted in breath, sweat and urine
<10%
what % of alcohol is metabolised in liver
> 90%
what enzyme catalyses the oxidation of alcohol to acetaldehyde
alcohol dehydrogenase
what is the issue with acetaldehyde and why
it is very toxic to the liver, it generates free radicals
what is acetaldehyde oxidised to
acetate
what are the fates of acetate once it has been metabolised from acetaldehyde
can enter krebbs cycle or be stored as fat
does exercise have an effect on alcohol clearance
doesn’t seem to have an effect
alcohol stimulates adrenaline secretion, what does this cause
- increased blood pressure
- increased risk of arrhythmias
- increased infraction risk
- ventricular weakening
alcohol vasodilates the skin, what does this increase the risk of
increased risk of hypothermia
long term effects on cardiovascular system from alcohol
long term weakening and stiffening of the heart
how does alcohol alter regulation of blood glucose and amino acids and what does this do
increasing adrenaline
- decreasing insulin
- increasing glycogenolysis in muscle and liver
what are the effects of alcohol decreasing innate immunity
the function of neutrophils and macrophages
- decreased oxidative burst
- decreased phagocyte function
what are the effects of alcohol decreasing adaptive immunity
decreased number of lymphocytes
what is the hormone that alcohol impairs causing it to be a diuretic
impairs anti diuretic hormone secretion
whether alcoholic beverages cause hypohydration depends on what
- existing anti diuretic hormone activity
- alcohol content in ingested fluid
- metabolism of alcohol
alcohol causes a miss match of perceived from …
perceived from actual competence
alcohol causes decreased vestibular …
function
how does alcohol affect sleep
decreases quality and duration
what happens to maximal and endurance performance due to alcohol
decreased maximal and endurance performance
what does alcohol do to the fuel availability in the blood
decreases fuel availability in the blood
what are the short term muscle responses to alcohol consumption
decreased recovery of force after eccentric damage
decreased synthesis of new protein after training
what are the long term muscle affects of alcohol consumption
oxidative damage
muscle atrophy
decreased capillarisation of fibres
what are the countermeasures to alcohol consumption
food will blunt the elevation in alcohol but exercise wont
