Lecture 32: Amino Acid Metabolism II Flashcards
3 intermediate molecules from Glycolysis used to synthesize amino acids
3-PG
PEP
Pyruvate
Intermediate molecules from TCA cycle used to synthesize amino acids
a-ketoglutarate
Oxaloacetate
Intermediate molecules from pentose phosphate pathway used to synthesize amino acids
Ribose-5-phosphate
Erythrose-4-phosphate
Non essential amino acids include
Cysteine C Alanine A Asparagine N Aspartic acid D Tyrosine Y Proline P Glutamic acid E Glycine G Serine S Glutamine Q
Essential amino acids include
Histidine Isoleucine Leucine Lysine Phenylalanine Threonine Tryptophan Valine (Arginine) (Methionine)
Oxaloacetate gives rise to ____, which gives rise to what other AAs
Aspartate
- Asparagine
- Methionine
- Threonine
- Lysine
Threonine gives rise to
Isoleucine
PEP + Erythrose 4-phosphate give rise to
Phenylalanine
Tyrosine
Tryptophan
Phenylalanine gives rise to
Tyrosine
Pyruvate gives rise to
Alanine
Valine
Leucine
Ribose-5-phosphate gives rise to
Histidine
a-ketoglutarate gives rise to ___, which gives rise to
Glutamate
- Glutamine
- Proline
- Arginine
3-PG gives rise to ___, which gives rise to
Serine
- Cysteine
- Glycine
_____ Donates an NH3 to ______ to form Asparagine
Glutamine donates NH3 to Aspartate
Aspartate can be used to synthesize Asparagine, lysine, threonine or methionine. Which AA is formed in the normal pathway without tight regulation
Asparagine is normally formed
Other organisms can modify aspartate to form lysine, methionine and threonine, and it is tightly regulated by feedback inhibition
