Lecture 3 Quiz: Innate Immunity 2 Flashcards
Which of the options below best completes the following statement: NK cells are of ___________ origin and target __________ for their elimination.
lymphoid, altered host cells … NK cells arise from a lymphocyte progenitor and attack virally infected and tumour host cells.
Which of the options below best completes the following statement: Perforin is a protein secreted by NK cells which……….
polymerise into channel-forming aggregates in the plasma membrane of target cells inducing osmotic lysis. —
Which of the options below best completes the following statement: NK cell cytotoxicity is mediated by…………..
a. activating signals. b. lack of inhibitory signals. c. expression of ligands that stimulate death receptors on target cells.
Which molecule below is a fungal pathogen-associated molecular pattern (PAMP)? a. Double stranded RNA. b. Lipopolysaccharides. c. Zymosan. d. Unmethylated CpG motifs.
Zymosan.
which pattern recognition receptor (PRR) gene family is expressed by innate immune cells?
TLRs are the main PRR family.
Which of the options below completes the following statement: Intracellular expression by innate immune cells is characteristic of…………
TLR3, TLR7 and TLR9. —– Incorrect, TLR4 and 5 are extracellularly expressed.
The definition, Innate and adaptive immune cell secreted protein that act as signalling molecules in an immune response corresponds to which of the following? a. Surfactants b. Cytokines c. Antimicrobial Peptides d. Lysozymes
cytokines orchestrate immune responses.
Leukocyte secreted cytokines, which act on leukocytes, are known as……..
interleukins are cytokines produced by leukocytes.
A cytokine that induces multiple effects on different immune cells is said to be……
A cytokine that induces multiple effects on different immune cells is said to be Pleiotropic.
An example of a cytokine produced by activated macrophages with a major role on the innate immune response is:
TNF is involved in systemic inflammation.
