Lecture 2 Quiz Flashcards
Which of the following innate immune response statements is false? a. Surface receptors of innate immune cells recognise pathogen associated molecular patterns. b. Results in the production of pathogen-specific antibodies and long term memory. c. Innate immunity enables rapid/immediate responses to invading pathogens. d. Includes internal defences such as phagocytosis of invading pathogens by innate immune cells.
. Results in the production of pathogen-specific antibodies and long term memory.
Which of the following statements is true for antimicrobial peptides (AMP)?
a. Enhance phagocytosis.
b. Preferentially bind eukaryotic membranes.
c. Perforate bacterial membranes to induce lysis.
d. Enhance phagocytosis and preferentially bind eukaryotic membranes.
c. Perforate bacterial membranes to induce lysis.
Which of the following statements is specific to gut chemical barriers? a. Specialized enzymes such as pepsin. b. Antimicrobial peptides. c. Lysozymes. d. None of the above.
Specialized enzymes such as pepsin.
Which complement pathway becomes activated by spontaneous hydrolysis of C3?
a. Classical
b. Alternative
c. Lectin
d. Both options a & b are correct
b. Alternative
The Alternative compliment pathway becomes activated by spontaneous hydrolysis of C3.
NOT CLASSICAL which is induced by C1q binding directly or indirectly to microbial surface
Complete the following sentence. The cleavage of C3 and C5 results in the production of C3a and C5a fragments which are…….
a. fundamental for the establishment of the membrane attack complex (MAC).
b. inactive molecules.
c. opsonizing agents.
d. anaphylatoxins.
d. anaphylatoxins.
…..
NOT C. the complement opsonizing fragments are C1q, C4b and C3b with its cleavage products.
Which of the following statements is true for Neutrophils?
a. Emigrate to tissues and become resident neutrophils with specialized functions.
b. Are the most abundant white blood cell (WBC) in peripheral blood.
c. Are the most efficient antigen presenting immune cell (APC).
d. Kill virally infected host cells by forming pores in their extracellular membrane.
Are the most abundant white blood cell (WBC) in peripheral blood. neutophils comprise 30-70% of peripheral WBCs.
Which of the innate immune cells below are not phagocytic? a. Lymphocytes b. Neutrophils c. Dendritic cells d. Macrophages
Lymphocytes
Which of the following statements best describes the classical complement pathway effector function?
a. Inflammation.
b. Pathogenic lysis.
c. Opsonisation.
d. All of the above.
d. All of the above. The activation of any of the classical complement pathways can give rise to the above effector functions.
Which complement component is involved in all complement pathways?
a. C9
b. C3
c. C1q
d. C4
C3 all complement pathways converge at the generation of C3 convertase.
Which of the following options best describes an opsonising agent?
a. Surfactants.
b. Antibodies.
c. C3b.
d. All of the above.
. All of the above. All of the responses above are examples of Opsonins.
Which is the least abundant granulocyte in peripheral blood?
a. Basophils.
b. Mast Cells.
c. Neutrophils.
d. Eosinophils.
Basophils. 0.1 – 0.3% of WBCs.
Which innate immune cell efficiently kills antibody coated parasites?
a. Macrophages.
b. Eosinophils.
c. Neutrophils.
d. Basophils.
Which innate immune cell efficiently kills antibody coated parasites? Eosinophils. binding of antibody-coated parasites by eosinophilic Fc receptors leads to the release of toxic granules that attack the pathogen.
