lecture 3 passive transport processes Flashcards
Simple diffusion
down concentration gradient (nonpolar)
primary active transport
against electrochemical gradient ATP used
Secondary active transport
against electrochemical gradient. energy comes from ions diffusing through the transport down their electrochemical gradient
facilitated diffusion
down electrochemical gradient gradient (transporter)
ion channel
ions down their electrochemical gradient. gated by ions or ligands
Ionophores
ions down their electronchemical gradient
types of transports in terms of the direction of the transport of ions?
1- uniporter; one ion
2- symporter:two ions same direction
3- antiporter: two ions opposite directions
Free diffusion of charged particles is
electroneutral:
In patch-clamping techniques, what is held constant and what is measured?
The transmembrane potential is held constant
and the current flowing across the membrane is measured
On-cell patch:
measures indirect effects of extracellular solutes on channels within the patch
Inside out detached patch
effects of intracellular solutes on channels within isolated patch
outside-out detached patch
Effects of extracellular solutes on channels within the isolated patch
outside-out detached patch
Effects of extracellular solutes on channels within the isolated patch
The neuronal Na+ channel is ……gated channel? How many domains with how many inactivation and activation gates? when is it active (polarised or depolarised?
Voltage og har voltage sensor.
4 domains
4 activation gates 1 inactivation gate.
when depolarised
what type of transporter is bicarbonate transporter?
It’s an antiporter. HCO3 + Cl
