Lecture 3 - Herpes/Fungal

Question 1

VZV:
transmission?
causes a _____ rash that starts on the _____ and spreads to the ______

Answer 1

respiratory;

vesicular, trunk, face/extremities

Question 2

VZV:
stays latent in the _____;
old age or _____ can cause shingles

Answer 2

DRG (or trigeminal ganglion);

immunosuppression

Question 3

name 2 complications from shingles

Answer 3

post herpetic neuraglia (Treat with gabapentin);

blindness (from V1 involvement)

Question 4

HSV1 is spread via _____;

HSV2 is spread via ______ or ______

Answer 4

resp secretions/saliva;

sex. perinatal (birth)

Question 5

HSV1 remains latent in the ______. HSV2 remains latent in the _____

Answer 5

trigeminal ganglia, sacral ganglia

Question 6

HSV1 or 2 causes....
gingivostomatitis = 
herpes labialis = 
genital herpes = 
keratoconjunctivitis =

Answer 6

HSV1;
HSV1;
HSV2;
HSV1

Question 7

HSV1 or 2:
erythema multiforme =
neonatal herpes =
temporal lobe encephalitis =

Answer 7

HSV1;
HSV2;
HSV1

Question 8

diagnosis of HSV:
us a _____ test. look for ____ cells;
what are cowdry A inclusions?

Answer 8

Tzanck, multinucleated;

intranuclear eosinophilic inclusions

Question 9

what 3 fungi cause tinea?

Answer 9

microsporum, trichophyton, epidermophyton

Question 10

tinea:
itchy or no?
treat most with ____;
what do you treat onchomycosis with?

Answer 10

yes;
azoles;
terbinafine or griseofulvin

Question 11

to visualize tinea, do a ______ prep.

dermatophytes are branching or non branching? septate or non-septate?

Answer 11

KOH;

branching septate hyphae

Question 12

what is said to have a spaghetti and meatball appearance on microscopy?

Answer 12

tinea versicolor = malassezia furfur

Question 13

which dermatophyte can you visualize with wood’s lamp?

Answer 13

microsporum

Question 14

candida:
often seen in patients with _____;
causes oral thrush that is scrapable or non scrapable?

Answer 14

diabetes;
scrappable

also diaper rash, angular chelotis

Question 15

candida vulvovaginitis:
what kind of discharge?
what is the pH?
name 2 risk factors

Answer 15

thick white (“cottage cheese”);
normal ie 4-4.5;
diabetes, OCPs, Antibiotics

Question 16

candida:
what do you treat oral thrush with?
what is specially used to treat vulvovaginitis?

Answer 16

nystatin;

fluconazole

Question 17

at 20 degrees, what does candida look like?

Answer 17

pseudohyphae with budding yeasts