Lecture 3: Development Flashcards

You may prefer our related Brainscape-certified flashcards:
1
Q

after ejaculation

A

sperm cells make their way through the acidic environment of the vagina to the more hospitable environment of the uterus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

ampulla

A

about 200 sperm cells reach the ampulla of the uterine tube. the ampulla is where fertilization occurs over a 24-hour period

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

acrosome

A

located at the tip of the sperm cell. contains enzymes that break down the outer layers of the egg cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

route of the sperm

A

the sperm and egg cell must fuse. the sperm must first pass through the layer surrounding the egg cell (corona radiata and zona pellucida). once past the barriers, the sperm cell leaves its plasma membrane and enter the cytoplasm of the egg cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

ootid

A

the egg cell that now contains the nuclei of the female and the male and has a haploid number of chromosomes from the sperm and the egg cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

capacitation

A

the process by which the sperm cell is prepared to enter the egg

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

zygote

A

when the fusion of the nuclei produces a diploid number of chromosomes it is then referred to as a zygote

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

diploid

A

the presence of two complete sets of chromosomes in an organism’s cells, with each parent contributing a chromosome to each pair

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

haploid

A

the presence of a single set of chromosomes in an organism’s cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

blastocyst

A

after 4-6 days, before implantation in the uterus, the mass of cells is called a blastocyst

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

stem cells

A

stem cells are undifferentiated cells that can turn into virtually any specialized cell. has two main types:
- embryonic stem cells
- adult stem cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

fission

A

the zygote single cells, or blastomere begins a series of mitotic divisions creating new cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

second week

A

by the end of the second week, the blastocyst implants itself into the uterus, the blastocyst nestles into the uterine wall, new cells must pass through the existing cells and layers. the cells build up from the inside out

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

around 9 to 10 weeks

A

the embryo develops teeth and nails

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

from 17 weeks

A

a baby can dream (REM sleep)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

end of pregnancy

A

the baby can close and open its eyes, however a lot can go wrong, such as ectopic pregnancy in the fallopian tube: the embryo must then be removed

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

totipotent stem cells

A

they can differentiate into all possible cell types

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

pluripotent stem cells

A

they can differentiate into most cell types

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

multipotent stem cells

A

they can differentiate into related cell types

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

oligopotent stem cells

A

they can differentiate into limited types of cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

unipotent stem cells

A

they can only differentiate into their own type of cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

invagination

A

when the embryo begins to assume its multicellular form during the gastrulation phase of the embryonic development. in this process, the folding of the embryonic cells produces three cell layers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

ectoderm (outer layer)

A

the layer of cell or tissue of an embryo in early development. the central nervous system forms from this

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

mesoderm (middle layer)

A

the layer of cells or tissues of an embryo. muscles, bones and connective tissues form from the mesoderm. the thicker cells in the mesoderm are called somites. this will later form the skeletal muscles

23
Q

progenitor cells

A

are similar to stem cells, but cannot divide as easily and they differentiate themselves into a specific type of cell. they lie next to the somites and will later form the spinal cord

24
Q

endoderm (inner layer)

A

the layer of cells or tissue of an embryo in early development. digestive and respiratory systems develop from the endoderm

25
Q

notochord

A

cylinder-like structure in the mesoderm that forms as a result of gastrulation, which arises from the primitive streak

26
Q

neural plate

A

the area of the embryonic ectoderm which all parts of the nervous system develop from. the neural plate further forms into the neural tube and the neural crest

27
Q

neurulation

A

the process by which the neural tube is formed

28
Q

spina bifida

A

the most common neural tube defect, where the lower neural tube fails to close. indiviuals with spina bifida may suffer from motor and sensory deficiets in the legs; incontinence, spinal curvature and increased cerbrospinal fluid pressure in the brain

29
Q

folic acid

A

can help with spina bifida along with surgery

30
Q

sonic hedgehog gene

A

a critical protein gene involved in signaling the development of the neural tube

31
Q

primary vesicles of the brain

A
  • prosencephalon (forebrain)
  • mesencephalon (midbrain)
  • rhombencephalon (hindbrain)
32
Q

migration

A

the process in which the cells of the brain arrive at their specific locations. the migrating neurons are immature and lack dendrites. the genetic code assigns each cell to its place

33
Q

radial glial cells

A

facilitates the journey of cells to a particular destination. radial glial cells provide a network of guiding cables and supporting structures that the migrating neurons uses to travel to its destination

34
Q

myelin

A

increases speed of neurotransmission, provided around some axons of neurons by glial cells

35
Q

myelination

A

begins in the spinal cord and progresses through regions of the brain. it is not limited embryonic development and continues into adulthood

36
Q

aborisation

A

when the neuron differentiates and forms into its final cell, the dendrites grow and create connection

37
Q

synaptogenesis

A

is final stage of development where formations of synapses happen. continues throughout life, but slows down in older age.

38
Q

synapses

A

while almost all neurons are formed prenatally, there are few synaptic connections. synapses depends on experiences and interaction with an environment - it is at the synapse where the learning occurs

39
Q

synaptic pruning

A

addresses the overproduction of synapses. synapses that are not being used are pruned. during childhood, pruning reduces the volume of grey matter in the cortex

40
Q

apoptosis

A

preprogrammed cell death. happens after migration

41
Q

nerve growth factor (NGF)

A

assists synaptogenesis. a protein that promotes the survival of only certain neurons

42
Q

Barker hypothesis

A

states that the development of disorders starts in the womb

43
Q

critical periods

A

life stages of an organism during which it is very sensitive to external influence

44
Q

axonal elaboration

A

learning increases dendritic innervation and arborization takes place

45
Q

synaptic elimiantion

A

pruning of many of the original embryonic axons, it is modulated by neuronal activity

46
Q

synaptic consolidation

A

a mechanism that strengthens the synapses with cell adhesion molecules (CAMs) that insert into synapses that have become strong

47
Q

thalidomide

A

most notable teratogen that has received widespread media attention. it is a drug used to treat morning sickness which is common in early pregnancy. the effects were that limb development was severely affected

48
Q

fetal alcohol syndrome

A

consumption of alcohol during pregnancy is very unwise as it can lead to malformation of the child’s brain

49
Q

three main features of FAS

A
  • facial abnormalities
  • growth disorder
  • mental impairment
50
Q

MRI studies of FAS

A

show that basal ganglia are less active in children with FAS. the corpus callosum appears to have abnormalities ranging from reduced size to complete absence and the volume of the cerebellum is reduced. also found asymmetry in the hippocampus, left temporal lobe was smaller than the right

51
Q

teratogens after birth

A

can still have a major impact on the individual. one example is air pollution: this is associated with changes in the brain that closely resemble abnormalities caused by Alzheimer’s disease

52
Q

cortisol

A

high maternal levels can cause high fetal cortisol levels

53
Q

neurotransmitters

A

high maternal cortisol may affect cell migration, neural development and synaptogenesis

54
Q

epigenetic changes

A

potentially transmissible changes without genetic modification: gene expression or gene inactivation

55
Q

genetic transmissibility

A

the mother’s genes can transmit susceptibility to the baby

56
Q

mature brain

A

during adolescence, the amount of grey matter in the brain continues to decrease while white matter increases (until about 40-50, then it decreases)

57
Q

cognitive reserve

A

states that when the brain is trained until late in life, symptoms of the reduction in white matter and brain volume are less present