LECTURE 3 Cells and Chromosomes Flashcards
All cells have
- DNA (genetic info)
- Ribosomes (make proteins)
Prokaryotes
—no nucleus
- Bacteria
- Archaea
Eukaryotes
Have nucleus and other organelles
Multicellular organisms (eukaryotes)
Every cell has the same DNA (information)
•Except?
red blood cells and gametes
Different cell types EXPRESS different genes
DIFFERENTIATION – cell is specialized
The Plasma Membrane
•Lipid bilayer with proteins and
carbohydrates
Selective Barrier
- Separates cell from the environment
- Lets some materials across to keep the cell functioning properly
- Similar structure for organelle
membranes
DNA + protein =
chromatin
Euchromatin=
- Loosely packed
- Interphase
- Active genes
Heterochromatin
- Tightly packed
- Metaphase
- Inactive genes
(Endoplasmic Reticulum)
Rough ER (RER)
- Bound ribosomes
- Synthesis of secreted proteins and glycoproteins
(Endoplasmic Reticulum)
Smooth ER (SER)
- Lipid Synthesis
- Membrane synthesis
Golgi Apparatus
- Polarized stack of membranes
- Enzymes modify proteins from ER
- Add & modify sugars
- Material moves between stacks via transport vesicles •Many final destinations
Protein synthesis occurs in different places Cytoplasmic proteins:
- Made of free ribosomes in the cytoplasm
- Proteins are soluble (hydrophilic)
Protein synthesis occurs in different places
Membrane proteins and secreted proteins:
- Made on ribosomes bound to the ER
- Sorted in the Golgi apparatus
- Membrane proteins are hydrophobic or amphipathic •Secreted proteins can be either hydrophilic or hydrophobic (or amphipathic!)
Lysosomes: Acidic organelles ?
Digest food & polymers to recycle monomers Phagocytosis and Autophagy