Lecture 28 Flashcards

1
Q

James watson

A

american chemist

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2
Q

Francis Crick

A

english molecular biologist

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3
Q

Rosalind franklin

A

British chemist and microphotographer

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4
Q

Maurice Wilkins

A

british researcher; discovered how to prepare uniformly oriented DNA fibers

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5
Q

Linus Pauling

A

was completely wrong about the structure of DNA

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6
Q

xray crystallography

A

x ray diffraction; crystals of a molecule are bombarded with a beam of xrays; the rays are bent (diffracted) by the molecules and the pattern is recorded on photographic film

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7
Q

Erwin Chargaff

A

nucleotide composition of DNA molecules vary in complex ways suggested that DNA was not a simple repeating polymer; discovered that ratio of A= ratio of T and ratio of C = ratio of G

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8
Q

Ball and stick models

A

watson and crick onoly built models and were viewed as lazy; watson went to franklin results report lecture as a spy and built a model but forgot the water content

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9
Q

X pattern

A

Franklin discovered the helix through the picture coming out looking like an X, but wilkins shows watson his picture; watson figured out helix based on that

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10
Q

nucleotide

A

3 main components: 5 carbon sugar, phosphate group (makes it an acid), and nitrogenous base

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11
Q

Adenine, Guanine

A

purine bases

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12
Q

Cytosine, thymine, uracil

A

pyrimidine bases

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13
Q

double helix

A

very stable with spacing of 3.4 angstroms

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14
Q

phosphodiester backbone

A

composed of alternating sugar and phosphate groups

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