Lecture 21 Flashcards
secretes epi and norepi
medulla
secretes corticosteroids
cortex
these are synthesized from cholesterol, and most attach to coated pits
corticosteroids
progesterone, aldosterone and cortisol are all
corticosteroids
this is a major mineralcorticoid and is secrete by the zone glomerulosa, secretion is controlled by angiotensin II and K+
aldosterone
this is the major glucocorticoid, secretion is controlled by ACTH, secreted by zona fasciculata, oscillates with circadian rhythm
cortisol
19-carbon steroids have androgenic activity and are precursors to ___
estrogens
what results from a decrease in aldosterone?
death, hyperkalemia
what results from an increase in aldosterone?
alkalosis, hypokalemia, muscle weakness
aldosterone ___ renal tubular reabsorption of Na and increases K+ in the urine
increases
ACE blocks the formation of
angiotensin
Ang II stimulates aldosterone secretin during Na
depletion
stimulates gluconeogenesis, may lead to adrenal diabetes, resists stress and inflammation, inhibits an immune response
functions of glucocorticoids
primary hypoadrenalism (addison’s) is due to an injury of what
adrenal cortex
secondary hypoadrenalism is due to impaired function of what
pituitary gland