Lecture 20 - Heart 2 Flashcards
Explain the Vaughnan Classification
Class I - Sodium Channel Blockers (disopyramide(Ia), lidocaine(1b) flecainide (1c)
Class II - Beta Blockers
Propranolol, atenolol, esmolol
Class III - Drugs that prolong the AP duration
Amiodarone, satalol
Class IV - CCBs verapamil, diltiazem
Name the anti-arrhythmic dugs outside of the Vaughan Williams Classification
Atropine
Isoprenaline
Adrenaline
Adenosine
Digoxin
MAgnesium sulfate
Name the two effects on the HR
Bradycardia
Tachycardia
Name the two effects on heart rhythm
Regular or irregular
Name the two sites of arrhythmias in the heart
Supraventricular (SAN, atria, AVN)
Ventricular (HIS bundles, Purkinje fibres, ventricles)
Name the two types of QRS complexes
Narrow complex
Broad complex
Name the types of supraventricular tachycardias (SVT) - most common
Paroxysmal SVT
Atrial fibrillation
Atrial Flutter
Name the types of ventricular tachyarrhythmias
Ventricular Tachycardia
Ventricular Fibrillation
these are the most dangerous
Name the pre-existing CV disease which cause tachyarrhythmias
Myocardial ischemia
Myocardial infarctions
Name the certain diseases and conditions which cause tachyarrhythmias
Congenital heart disease
Hyperthyroidism
Pheochromocytoma
Name other causes of tachyarrhythmias
Electrolyte imbalance - hypokalaemia
Drugs:
inhalers
anti-arrhythmic drugs
Anti-hypertensives
Anti-fungal drugs
Antibiotics
Antihistamines
Name the genetic disorders which cause tachyarrhythmias
Channelpathies - mutations in cardio voltage activated Na+, Ca2+, K+ channels and associated proteins
- Long QT syndrome
- Bruganda Syndrome
Abnormal conduction pathways in the heart - Waff Parkinson-White (WPW) syndrome
Storage and release of Ca2+ from the SR - CPVT (Catecholaminergic Polymorphic Ventricular Tachycardia)
