Lecture 20 And 21 - The Enery Distribution System Flashcards
The Energy Distribution System
Energy is defined as the capacity to do work
ATP - Adenosine Triphosphate
The medium of energy exchange - energy currency of the cell
Reducing Equivalents
Glycolysis, beta oxidation and Kreb’s Cylce produce NADH and FADH2 (supply protons and electrons to the ETC)
Anaerobic ATP Production
- Phosphocreatine degradation
- Glycolysis (end product is lactate in anaerobic conditions)
- inefficient but fast
- ATP is rebuild by adding a phosphate to ADP
Fat
most energy is stored as triglycerides in our adipocytes (fat cells in adipose tissue)
Carbohydrate Stored as:
- Liver: Glycogen (overnight)
- Muscle: Glycogen (during exercise)
Protein
- large potential energy source
- used during starvation or caloric restriction
Pro of Carbohydrates
- Aerobically can generate ATP slightly faster than from fat
- Can also generate ATP anaerobically (3x faster)
- good for long exercise (storing glucose for later so skeletal muscle isn’t used)
Con of carbohydrate
Holds a lot of water
Pro of Fat
- doesn’t hold water, twice as energy dense as carbohydrate
- represents our most abundant energy reserve
Cons of Fat
Can’t provide energy anaerobically
Absorptive State
- first 3-4 hours after a meal
- energy (macronutrients) are stored (anabolism)
- excess calories in the form of glucose or amino acids can get converted to fat
Post absorptive state
- fasting
- stored macronutrients are mobilized for energy (catabolism - break down of macronutrients)
- glucose is spared for nervous system
Gluconeogenesis
Making glucose from non-carbohydrates precursors
Normal Fasting Blood Glucose
4 - 5.5 mM