Lecture 2: Parasite Immunity Flashcards
Intensity
Quantity of parasites infecting a host (often using mean intensity)
Prevalence
Fraction of hosts infected at a given time
Incidence
Number of new infections per unit of time divided by the number of uninfected individuals at the beginning of the measured time (often used incorrectly to refer prevalence)
Density
Average number of parasites per sampling unit
Immunity
Includes specialized tissues capable of recognizing and protecting against non-self invaders
Resistant Host
Noninfective pathogen
Susceptible Host
Infective pathogen
Innate Immunity (First Line of Defense) Characteristics
Non-specific, no prior exposure, no memory reponse
Premunition
An incomplete response, there is a failure of the immune system to complete rid host of a pathogen. However, there is recovery from disease symptoms and resistance to further damage
Concomitant Immunity
An incomplete response in which the pathogen confers immune response which prevents reinfection. However, pathogen still remains in the body unaffected.
Acquired Immunity Characteristics
Specific, memory response
Cell Mediated Immunity
Acquired immunity that involves cytotoxic T cells which kill infected cells
Humoral Immunity
Acquired Immunity that involves antibody production by B cells against specific antigen
Phagocytosis (Endocytosis)
Process of engulfment of the invading particle within an invagination of the phagocytes cell membrane (Examples: Granulocytes and Macrophages)
How is inflammation via innate immunity mediated?
By cytokines and the complement cascade. Activated macrophages, granulocytes, and T-lymphocytes are involved
