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AU2017 Oral Micro Final > Lecture 2- Oral microbiota and systemic connections > Flashcards

Lecture 2- Oral microbiota and systemic connections Flashcards

1
Q

2 direct mechanisms for oral connections

A

translocation of bacteria (seeding)

translocation of toxin

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2
Q

in infective endocarditis, … and … adhere to exposed connective tissues producing …

A

platelets and fibrin

nonbacterial thrombotic endocarditis (NBTE)

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3
Q

When a patient has NBTE, bacteria from the oral cavity can …

A

enter bloodstream and adhere to NBTE

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4
Q

What can the bacteria do once it adheres to NBTE in heart

A

multiply, infiltrate heart tissues and cause cardiac and valvular injury

emboli and stroke if dislodged

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5
Q

3 types of oral bacteria involved in infective endocarditis

A

streptococci (sanguis, mitis, mutans)

A.Actinomycetemcomitans

Gemella

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6
Q

skin bacteria involved in infective endocarditis

A

staphylococci

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7
Q

T/F there is solid evidence that dental procedures are associated with IE

A

false

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8
Q

Is antibiotic prophylaxis during dental procedures likely to prevent cases of IE?

A

no

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9
Q

whats the best way to reduce the risk of IE

A

regular good oral hygiene

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10
Q

what is the leading cause of death from infection in those over 65

A

aspiration pneumonua

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11
Q

aspiration pneumonia is caused by…

A

aspiration of oral secretions (oral bacteria)

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12
Q

aspiration pneumonia is common in the … and …

A

physically handicapped

elderly

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13
Q

oral hygiene measures can reduce nosocomial pneumonia by … %

A

40

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14
Q

oral hygiene measures could prevent … % of deaths in elderly in nursing homes

A

10

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15
Q

T/F periodontitis is associated with preterm birth, low birthweight and pre-eclampsia

A

true

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16
Q

T/F randomized clinical trials show periodontal treatment reduces risk of PTB or LBW

A

false

17
Q

T/F treatment of periodontitis improves glycemic control

A

true

18
Q

… and other perio pathogens found in atherosclerotic lesions

A

p. gingivalis

19
Q

… exacerbates CVD in animal models

A

p. gingivalis

20
Q

there is an increased prevalence of … in diabetics

A

periodontitis

21
Q

coronary heart disease, stroke, PVD are all associated with … but the association is modest and there has not been a causative relationship established

A

periodontitis

22
Q

studies show increased risk of … cancer in patients with periodontitis

A

pancreatic

23
Q

cardiovascular implantable electronic device (CIED) infections are caused by bacteria from …

A

skin of patient or hands of hospital workers

24
Q

T/F the AHA guideline for nonvalvular cardiovascular device-related infections recommend antibiotic prophylaxis for dental treatment

A

false

25
Q

for vascular grafts/stents, most infections (90%) are caused by bacteria native to … or …

A

skin or bowel

26
Q

T/F CDC guidelines for the prevention of intravascular catheter-related infections recommend prophylaxis antibiotics

A

false. do NOT give AP for any reason

27
Q

… % of joint prostheses become infected and there is a … morbidity

A

1-2%

high

28
Q

there is a lack of evidence supporting …. to reduce dental procedure related bacteremia and distant site infection in a joint prostheses

A

secondary antibiotic prophylaxis

29
Q

there is evidence for …. at the time of placing a joint prostheses unrelated to dental treatment

A

primary antibiotic prophylaxis

30
Q

late infections in joint prostheses from … can occur

A

hematogenous seeding

31
Q

the bacteria responsible for infection of a joint prostheses is most often….

only …% of the time is it from bacteria found in the oral cavity

A

staphylococci

5%

32
Q

T/F there is no indication for antibiotics to prevent oral bacterial source for patients with pins, plates and screws

A

true

33
Q

is there evidence that microorganisms associated with dental procedures cause infection of cerebrospinal fluid shunts?

A

no

34
Q

conditions associated with direct transfer of oral bacteria

A

IE

pneumonia in immunocompromised

immunosuppression

preterm birth?

35
Q

primary preventative strategy for reducing risk of transfer of oral bacteria in the following conditions: immunosuppression, IE, PTB, pneumonia

A

improve oral health and reduce bacterial load

antibiotic prophylaxis indicated in specific high risk situations

36
Q

conditions associated with the transfer of oral bacteria or toxin or common inflammatory pathway

A

type 2 diabetes

CV disease

pancreatic cancer

37
Q

what are the primary preventative strategies to prevent transfer of oral bacteria toxin

A

treat periodontal disease to improve microbial profile

improve overall health by addressing risk factors

38
Q

7 conditions where there are no special oral precautions since there is not evidence that oral bacteria is the cause

A 
CIED
vascular grafts/shunts
prosthetic joints
bone pins, plates, screws
renal dialysis shunts
CSF shunts

AU2017 Oral Micro Final (10 decks)

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