Lecture 2: Membrane Biophysics

Question 1

What are P-Type ATPases? What is their function?

Answer 1

The phosphorylation and dephosphorylation changes are responsible for ion transport. The goal s to optimize resting ion concentrations 3 types: Na,K-ATPase, Ca-ATPase, H,K-ATPase

Question 2

How can cells convert chemical potential energy (ATP) to other types of chemical energy?

Answer 2

Through the generation of ion gradients. Can be used for things like secondary active transport and can convert chemical energy to electrical energy.

Question 3

What is the Ca-ATPase? What does it do?

Answer 3

A P-Type ATPase. They regulate the concentration of calcium in cells. two types: Plasma membrane Ca-ATPase and Sarco-Endoplasmic Reticulum Ca-ATPase. Both pump Ca out of cell and transport protons as counterions.

Question 4

What is H,K-ATPase? What does it do?

Answer 4

Functions by pumping two protons and two counterions. It is primarily involved in acid secretion by specialized cells in the stomach and kidney.