Lecture 2: Cells of the Immune System Flashcards
1
Q
What are the two niches in which hematopoietic stem cells can self-renew?
A
1) osteoblasts 2) sinusoidal endothelial cells
2
Q
What do stromal cells do in the bone marrow?
A
provide factors needed for HSC maintenance and differentiation into peripheral blood progenitors
3
Q
What are the two options for HSC to differentiate into first?
A
1) common myeloid progenitor 2) lymphoid progenitor
4
Q
What do Common Myeloid Progenitors differentiate into?
A
Thrombocytes, RBCs, granulocytes, or monocytes
5
Q
A
