Lecture 2 Flashcards
Stroke
Brain Attack, CVA, Mini-Stroke, Pin Stroke, and TIA (transient ischemic attack- brief and passing)
- Strokes are preventable
- Strokes in the right hemisphere affect the left side of the body
- TIA- indicative of larger stroke (coming)
Stroke Awareness
- 19% are unaware that stroke is preventable
- 38% do not know where in the body a stroke occurs
- 42% cannot identify the most common s/s of stroke is weakness/numbness
- 92% do not realize what a TIA represents
Stroke Defined
- Describes the clinical consequences of a focal or diffuse disruption of brain circulation secondary to an ischemic or hemorrhagic event
- Interruption of blood flow in the brain
50% of the general population is at risk
> 50% of healthcare workers are at risk (stress)
-90% of stroke suvivors has chronic deficits (such as dysarthria)
Stroke Statistics
- 3rd leading cause of death in the USA
- Heart Disease is #1; Cancer is #2
- 750K new cases each year; 500K are preventable
- Roughly 1 every 45s
- Every 3m a person dies from stroke
- Leading cause of disability; 90% of survivors have deficits
80%of strokes are Ischemic
20% of strokes are hemorrhagic
Stroke Epidemiology
Age-
Risk of stroke doubles each decade after 55y
Race-
African Americans: 233/100K
Hispanics: 196/100K
Whites: 93/100K
Heredity-
Paternal Stroke: 2x as likely for stroke
Maternal Stroke: 1.4x as likely for stroke
Time is brain
- 2 million brain cells die every minute during a stroke
- 80% of strokes are preventable
- Based on ~730K strokes annually
- Decrease heavy alcohol use: 34K
- Decrease smoking: 90K
- Decrease cholesterol: 145K
- Decrease Hypertension: 360K; 130/85 is HTN
- Every minute you wait during a stroke is neurons dying
Atrial Fibrillation
- AF- irregular heart beat
- Risk factor for stroke. Rapid heartbeat (tacacardia)
- AF is a type of irregular heartbeat resulting in ineffective pumping of one of the chambers of the heart (causes ischemic strokes)
- Impacts 2 million Americans
- 9% of persons age 65y+ have AF
- s/s: rapid heartbeat, irregular heartbeat
- tx: blood thinners; proper tx prevents stroke
- 4 chambers in the heart. Quivering in the heart causes a clot and the clot can be sent to the brain
Risk Factors for Stroke
- Diabetes
- Physical Inactivity
- Obesity
- Metabolic Syndrome)
- Oral Contraceptives
- Alcohol Abuse
- Illicit Drug Use
- Hypercoagulable States
- Dietary Factors
- Infection/Inflammation
- Hyperhomocysteinemia- leads to vascular inflammation
- Vascular Inflammation
Modifiable Risk Factors for Stroke
- DM- diabetes mellitus
- HTN- hypertension
- Smoking
- Alcohol Consumption
- Obesity/Overweight
- AF
- High Cholesterol
Non-Modifiable Risk Factors for Stroke
- Age
- Race
- Gender
- Previous TIA/CVA
- Family Hx
Common Stroke Symptoms
- Weakness: Sudden numbness or weakness of face, arm or leg, especially on one side of the body.
- Speech/Language Disturbances: Sudden confusion or trouble in speaking or understanding speech.
- Visual symptoms: Sudden trouble seeing in one or both eyes
- Motor symptoms: Sudden trouble in walking, feeling dizzy or loss of balance and coordination
- Severe Headache: Sudden and severe headache with unknown cause
Have these: go to the hospital
Rapid Detection of Stroke
- Acronym FAST
[F] FACE: Ask the Patient to smile; Any drooping?
[A] ARM: Ask the Person to raise both arms; Any drifting?
[S] SPEECH: Ask the Person to repeat simple sentences; Any dysarthria?
[T] TIME: Observe any signs; Call 911!
make sure patient is not hypoglycemic- low sugar can mimic stroke signs
Stroke Classifications
- Ischemic- 80%
- Hemorrhagic- 20% (more deadly- blood should never interact with the brain) violation of MKH
- —-SAH- subarachnoid hemorrhage
- —-ICH- Intracerebral hemorrhage
- —-IVH- Intraventricular hemorrhage
Ischemic Strokes
Occur when arteries are blocked by blood clots or by the build up of plaque and other fatty deposits
As such, blood flow is insufficient to a given area
80%+ of strokes are ischemic in nature
•Ministroke, pin stroke, TIA- brief occlusion of a vessel.
large and small vessels
2 Types of Ischemic Strokes
Thrombotic: blood clot forms within a blood vessel in the brain; vessel supplying blood to the brain (Stationary)
Embolic: blood clot forms with in the heart or elsewhere, dislodges, and becomes lodged in the brain (moves)
Lacunar Infarct (Ischemia)
Obstruction of blood flow in the small, deep brain arteries; occur frequently in the Basal Ganglia, Internal Capsule, Thalamus, Brain Stem!
o Lacunar- stoke occurs in small, deep brain arteries. Causes focal damage. Often occur in subcortical areas (basal ganglia, internal capsule, brainstem)
Ischemic Penumbra
The penumbra is an area of dysfunctional ischemic tissue; suggests a possible lacunar state. Can use tPA with ischemic strokes
o Penumbra- tissue around the blood clot (hypoprofused- blood cannot reach area)
Hemorrhagic Strokes
- Occurs when a blood vessel in the brain breaks leaking blood into the brain; accounts for ~15-17% of all stroke but are responsible for more than 30% of deaths
- Intracerebral Hemorrhage
- Subarachnoid Hemorrhage
- Intraventricular Hemorrhage
•A small bleed in the brain (the body will absorb the blood) Astrocytes will help clean up the bleed.
Intracerebral Hemorrhage
- Bleeding inside the brain
- Results from chronic HTN
- Often coincides w/severe headaches
blood is moving faster and puts strain on the blood vessels
Subarachnoid Hemorrhage
- Bleeding that occurs within the meninges
- Possible rupture of an aneurysm
- Sudden headaches with LOC
- Women>Men
in the subarachnoid space- can suck the blood out at times or the brain may be able to reabsorb the blood