Lecture 19: Clinical gynaecology Flashcards

1
Q

At point does gynaecology health become important?

A

Its important across all her lifespan

Hospital and community settings for womans health issues are very different

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2
Q

What does clinical gynaecology involve?

A
  • Education i.e whats normal, what to expect
  • Prevention (Smear)
  • Diagnosis and treatment of disease
  • Managing symptoms
  • Bening and malignant pathologies
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3
Q

When you have a young female come into a GP clinic, what are some things worth asking?

Note different ages have different needs

A
  • Sexually active?
  • Explore need for contraception
  • Educate regarding family planning and sexual health
  • Screen for family violence
  • Offer cervical smear and self swabs for STI screen
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4
Q

What are some long acting reversible contraception options? discuss benefits

A

LARCs

  • Effective, reversible, long lasting contraception
  • Do not rely on patient compliance
  • Failure less than 1%
  • Cost effective

Methods:
- Subdermal contraceptive implant i.e jadelle, copper IUD, hormonal IUD, DEPO (lasts only 3 months tho)

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5
Q

Why cervical smear?

A
  • Cervical cancer caused by HPV
  • Slow progressive change over ten years
  • Smear detects precancerous cervical change
  • 20-69 y/o that are sexually active are invited to smear every 3 years

Note will be changing to HPV screening

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6
Q

Where does cervical cancer occur?

A

Majority of cancer developed within the transformative zone

= Area of maturing epithelium b/w current squamocolumnar junction and the original squamous epithelium

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7
Q

Describe the smear test:

A
  • Use of speculum to visualise the cervix

- Cytobroom to sample cells from transformative zone

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8
Q
  • 36 year Pacific woman sees GP with heavy periods lasting 10 days with ‘flooding’
  • Menarche age 12, always had heavy periods, worse last 2 years, no IMB/PCB, no pelvic pain
  • Feeling tired and exhausted
  • Wants to get pregnant
  • Normal smear history

How do you proceed with her tiredness?

A

•Screen and treat anaemia
- Iron deficiency anaemia confirmed (Hb 92, ferritin 6)
Treat : oral iron or iron infusion

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9
Q
  • 36 year Pacific woman sees GP with heavy periods lasting 10 days with ‘flooding’
  • Menarche age 12, always had heavy periods, worse last 2 years, no IMB/PCB, no pelvic pain
  • Feeling tired and exhausted
  • Wants to get pregnant
  • Normal smear history

How do you exclude other pathologies?

A

Exclude pathology

  • Normal gynaecological exam
  • Normal pelvic ultrasound
  • Normal endometrial sampling
  • Negative pregnancy test
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10
Q
  • 36 year Pacific woman sees GP with heavy periods lasting 10 days with ‘flooding’
  • Menarche age 12, always had heavy periods, worse last 2 years, no IMB/PCB, no pelvic pain
  • Feeling tired and exhausted
  • Wants to get pregnant
  • Normal smear history

What pre-pregnancy advice do you give?

A

•Pre-pregnancy advice

  • Start folic acid and iodine, stop smoking
  • BMI into healthy range if not already
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11
Q

How do you perform a gynae exam?

A

Abdo palpation - Pelvic masses i.e pregnancy, tumour

Speculum examination - Visualise cervix, swabs/STI screen, smear if indicated

Bimanual examination (fingers in vagina, push down on uterus)
- uterine size and position, mobility and tenderness, adnexal masses (tubes)
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12
Q

How is pelvic ultrasound performed and what does it diagnose?

A
  • Transvaginal or transabdo
  • Visualise cervix, uterus, adnexae
  • Diagnosis of polyps, fibroids, ovarian cysts, pelvic abscesses
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13
Q

What are the treatments for heavy menstural bleeding?

A
  • Depends on age, fertility plans, choice i.e hormones (contraceptives) or surgery i.e hysterectomy or endometrial ablation
  • Can manage with NSADIS and/or tranexamic acid to allow for pregnancy
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14
Q

What does tranexamic acid do?

A
  • Tranexamic acid binds to plasminogen
  • Blocks interaction of plasminogen with fibrin
  • Prevents dissolution of fibrin clot
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15
Q

Write some notes on endometrial ablation:

A
  • Day case procedure
  • Short recovery time
  • 2/3rds women satisfied
  • 1/3rds require repeat procedure or hysterectomy

Insert probe into uterus and ablation of the endometrium

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16
Q

Whats the risk and prognosis for a hysterectomy?

A
  • Major procedure with significant risks:Bleeding, Infection, Damage to bladder/bowel/ureter,Re-operation, Chronic pelvic pain/adhesions, Blood clots
  • Requires 6-8 weeks recovery (regardless of route)
  • High satisfaction rate overall
17
Q
  • 52 year old Asian women with night sweats and hot flushes since her periods stopped 18 months ago
  • Unable to concentrate at work due to tiredness, feeling low and wanting to reduce her working hours

What are you going to do?

A

Educate regarding menopause, check for other symptoms, discuss treatment options :

  • Explain she is now postmenopausal (Definition of menopause =1 year from LMP)
  • Outline physical and psychological symptoms
  • Mean duration of vasomotor symptoms is 2 years for majority of women
  • Screen for depression/mental health

•Health promotion: mammogram & cervical screening history, advice regarding breast awareness, PMB, bone health, CVS risk

18
Q

What is menopause and what symptoms are common?

A
  • ‘Normal’ life transition stage-not disease
  • 10% women need medical assistance
  • Vasomotor symptoms due to loss of oestrogen, self-limiting
  • 50% women experience local genital symptoms which persist-pain with sex, bladder urgency and recurrent UTI’s-treatable with local oestrogen cream/pessaries
19
Q

What are the treatment options that can help with menopause?

A
  • Symptom control!!
  • Lifestyle measure to reduce hot sweats/CVS/prevent osteoporosis: weight loss if obese, weight-bearing aerobic exercise, reduce caffeine/alcohol, stop smoking
  • Non-hormonal treatment includes SSRI/SNRI, gabapentin (Vasomotor), CBT
  • Hormone treatment-if no contraindications-use lowest dose for shortest duration
20
Q

Whats the risk of hormone replacement therapy?

A

DVT, stroke, gallbladder disease

21
Q
  • 28 year old women with increasing pelvic pain, worse just before period starts, with pain on having sex (dyspareunia)
  • Pelvic examination reveals deep vaginal tenderness to right side, pelvic ultrasound a 3cm right ovarian cyst

What are you going to do?

A
  • Discuss potential diagnosis and treatments..
  • Discuss symptoms of endometriosis
  • Severity of symptoms and impact on life (work, relationship, mood)
  • Plans for having children
  • Medical versus surgical treatment options
22
Q

What are the symptoms of endometriosis?

A
  • Painful periods
  • Painful sex
  • Pain on opening bowels
  • Pain on passing urine
  • Mid cycle / ovulatory
  • Chronic pelvic pain
  • Delayed conception
23
Q

How does endometrioma (endometriosis of the ovary) appear on ultrasound?

A

Grainy appearance of cyst contents due to altered blood

24
Q

What are the facts of endometriosis?

A
  • Affects 1 in 10 women in reproductive years
  • Chronic condition, Progresses.
  • No pain to severe, i.e spectrum
  • 40% of women with infertility have endometriosis
  • No known cause, genetic predisposition
25
Q

Whats the pathology of endometriosis?

A
  • NOT normal endometrium displaced into ‘wrong’ place RATHER deposits of glandular tissue that cause chronic inflammation, scar tissue and smooth muscle infiltration
  • Inflammation promoted by hormonal cycles
  • Sites involved: peritoneum, ovaries, tubes, bladder, bowel, rectovaginal septum
  • Diagnosis requires laparoscopy with biopsies
26
Q

How is endometriosis managed?

A
  • Manage pain
  • NSAIDS and hormonal suppression (Hormonal contraceptives) reduces inflammation
  • Surgery aims to excision deposits of endometriosis, not always possible due to location (e.g. close to ureters/bowel) - must consider fertility wishes
  • Surgery often repeated, increasing complexity

NB: Hysterectomy is not curative

27
Q

What are ovarian cancers?

A

Not one disease but many

  • 90% cases are malignant epithelial tumours
  • Non-specific symptoms…. so high index of suspicion required
  • 90+% cases have elevated Ca125 levels
  • Most present with advanced disease
28
Q

Whats the usual treatment for ovarian cancer?

A

Major surgery and chemo

29
Q

What can be done for the early detection and prevention of ovarian cancer?

A
  • Combined pill for five years reduces risk by 50%
  • Pregnancy <26 years and breastfeeding reduces risk
  • Awareness of family history and genetic referral
30
Q

What is familial ovarian cancer?

A

BRACA 1 and 2 predispose people to ovarian cancer

Serum tumour marker Ca125 and pelvic US can serve as screening

Prophylatic removal of both ovaries and tubes ones family is complete