Lecture 18 Flashcards
What percent of the dry weight of the human body is composed by proteins?
44%
Proteins are what percent of our caloric intake?
5%
What are polysomes?
String of ribosomes translating a single messenger RNA
Which way does protein syntheses occur?
N to C
What is the name of the type of mutation that results in a stop codon?
nonsense
Eukaryotic ribosomal units?
- 60s and 40s
- total 80s (doesn’t add but it is what it is)
What are the accessory RNA units for eukaryotes?
- 5s, 28s, 5.8s
Prokaryotic ribosomal units?
- 50s and 30s
- total 70s
What are the accessory RNA units for prokaryotes?
- 16s
How many antibiotics are used to disrupt translation?
About half
How many antifungal affect process of translation?
None because fungal translation is so similar to human translation that it is difficult to find an agent that will disrupt fungal translation without fucking up ours.
how many antivirals affect translation?
none yet
what is the shape of eukaryotic mRNA and how?
circular due to the 4e protein that binds the 5’ cap and the Pab1 protein that binds the polyA tail (Pab1 and 4e are connected)
eukaryotic mRNA is ____-cistronic.
mono-
what does mupirocin do?
it is an antibiotic that inhibits isoleucine-tRNA synthase in bacteria
