Lecture 17 Flashcards
Signal Transduction Stages
1) binding ligand to receptor
2) signal transduction vis 2nd messengers like cAMP, calcium or G-protein
3) cellular response
- cellular growth, cell division, store glucose molecules as glycogen
Where does epinephrine bind to?
liver cell receptor
ECM components**
- produced by cells assembled into a network
- major components are proteins like glycoproteins
What do double-layered folds: cristae do?
-increase membrane surface area and contain machinery for aerobic restoration and ATP formation
Extracellular Matrix (ECM) Functions
- cell adherence
- communication between cells
- cell shape, mechanical support, structural integrity
- serves as barrier, filters out some particles
Process of epinephrine becoming glycogen
- active receptor will recruit g-protein and allow binding of GTP to turn on
- front bottom section of G-protein dissociates and turns ON enzymes called adenyl cyclase which cause cAMP accumulation inside cells
- at the end, phosphorylase- P is an enzyme that releases glucose units
What are multicellular organisms?
composed of tissues and organs consisting of communities of cells to work together to perform functions
What do cells of bacteria, plants and fungi have?
Walls
What is cellular respiration?
- uses chemical NRG stored in molecules like carbohydrates and lipids to produce ATP
- involves a series of catabolic reactions
What is photosynthesis?
- building carbohydrates using sunlight and CO2 NRG
What is oxidative phosphorylation?
- oxidative phosphorylation is stage 4 in animal cell cellular respiration
- divided into 2 steps
What is the point of glycogenolysis?
- how epinephrine activates conversion of glycogen stored in liver to glucose
What are porins?
- large channels permeable to many molecules when opened
What is phospholipid cardiolipin?
- characteristic of bacterial membranes and needed for optimal function of many enzymes
What is substrate-level phosphorylation?
- hydrolysis reaction releases enough NRG to drive the phosphorylation of ADP to ATP