Lecture 16 Flashcards

1
Q

Membrane structure is held together by:

A

Hydrogen bonds

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2
Q

Lipids rarely flip flop between membrane leaflets therefore the lipid composition of the leaflets can be asymmetric. T/F?

A

True

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3
Q

How does lipid tail length affect the fluidity of the membrane?

A

The longer the tail, the less fluid the membrane

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4
Q

How does the number of double bonds affect the fluidity of the membrane?

A

More double bonds increases fluidity

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5
Q

How does the amount of cholesterol affect membrane fluidity?

A

More cholesterol decreases fluidity

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6
Q

Integral proteins are:

A

Proteins that extend into or completely across cell membrane (transmembrane)

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7
Q

Peripheral proteins:

A

Attached to either the inner or outer surface of cell membrane and are easily removed from it.

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8
Q

Integral proteins polarity:

A

amphipathic

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9
Q

Functions of membrane proteins (x6)

A

Receptor, cell identity markers, linkers, enzymes, ion channels, transporters

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10
Q

Channel proteins:

A

Allow specific substances to move through water filled pore.

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11
Q

Transport proteins:

A

Transport specific substances across membrane by changing shpa.e Amino acids enter body cells via transporters.

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12
Q

Selective permeability of membrane: (x4)

A

Permeable to nonpolar, uncharged molecules. Permeable to lipid soluble molecules. Permeable to small uncharged polar molecules.

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13
Q

Impermeability of membrane:

A

-Impermeable to large uncharged polar molecules.

Impermeable to ions.

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14
Q

The greater the difference in concentration between the 2 sides of the membrane, the ______ the rate of diffusion.

A

faster

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15
Q

The higher the temperature, the _____ the rate of diffusion

A

faster

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16
Q

An increase in surface area, _______ the rate of diffusion

A

increases

17
Q

Increasing diffusion distance, ___ rate of diffusion

A

slows

18
Q

What is 1 outcome of a cell increasing the membrane area available for diffusion?

A

increases diffusion

19
Q

How does membrane thickness affect diffusion

A

Slows

20
Q

Diffusion is very fast over ___ distances

A

small

21
Q

Movement of ions will be influenced by the _____ _____

A

electrical gradient

22
Q

What enables a difference in concentration gradient across the membrane to be established?

A

The selective permeability. The difference in charged ions between the inside and outside of membrane establishing an electrical gradient.

23
Q

Osmosis:

A

diffusion of water across membranes.

24
Q

Osmosis only occurs when:

A

Only occurs if membrane is permeable to water but not to certain solutes.

25
Q

Define Pw, Pd, and Pf.

A

Pw = membrane permeability to water. Pd - permeability of lipid bilayer. Pf- permeability of water channel/aquaporins.

26
Q

Pw eq

A

Pw = Pd + Pf. Pf > Pd

27
Q

Water channels are also called

A

aquaporins

28
Q

Properties of Pd

A

Small, mercury insensitive, temp dependent

29
Q

Properties of Pf

A

Large, mercury sensitive, temperature independent

30
Q

Osmotic pressure is:

A

the pressure applied by a solution to prevent the inward flow of water across a semi-permeable membrane

31
Q

If the solution has the same osmolarity it is:

A

isosmotic

32
Q

If the solution has a lower osmolarity it is

A

hyposmotic

33
Q

If the solution has a higher osmolarity it is:

A

hyperosmotic

34
Q

What kind of solution causes cell swelling and lysis?

A

Hypotonic

35
Q

What kind of solution causes cell shrinkage (crenation)?

A

Hypertonic