Cell Processes Lecture 1 Flashcards
Fluid mosaic model:
“Sea of lipids in which proteins float like icebergs
Membrane is held together by _____
hydrogen bonds
The lipid is a ____
barrier to entry or exit of polar substances
Lipid bilayer:
Proteins are inserted into different areas of the bilayer. Two back to back layers of 3 types of lipids molecules. Cholesterol and glycolipids scattered among a double row of phospholipid molecules.
Phospholipids polarity:
Amphipathic
Lipids flip flop:
Rarely between membrane leaflets therefore the lipid composition of the leaflets can be asymmetric.
Fluidity is determined by:
- Lipid tail length (the longer the tail, the less fluid)
- Number of double bonds - more double bond increases fluidity
Amount of cholesterol - more decreases fluidity
Membrane proteins: (2 types)
Integral proteins: extend into or completely across cell membrane (transmembrane protein)
-Peripheral proteins: attached to either inner or outer surface of cell membrane.
Integral membrane proteins x3:
-Amphipathic
Functions of membrane proteins:
- Receptor proteins
- Cell identity markers
- Linkers
- Enzymes
- Ion channels
- Transporter proteins
Channels:
-Allows specific substance move through water filled pore. Most plasma membranes include specific channels for several common ions.
Transporters:
Transports specific substances across membrane by changing shape.
Selectivity permeability:
Permeable to nonpolar, uncharged molecules.
Permeable to small uncharged polar