Lecture 16 3/26/24

Question 1

Which antimicrobials cannot be given orally to hindgut fermenters?

Answer 1

-penicillin
-lincosamides
-amoxicillin
-cephalosporins
-erythromycin

Question 2

What does the dose interval depend on for a time-dependent antimicrobial?

Answer 2

-MIC
-half-life

Question 3

What does the dose interval depend on for a concentration-dependent antimicrobial?

Answer 3

-MIC
-post-antibiotic effect

Question 4

What are the characteristics of mycoplasma treatment?

Answer 4

-no beta-lactams bc they lack a cell wall
-can treat with macrolides, tetracyclines, lincosamides, fluoroquinolones, ‘amphenicols

Question 5

Which fluoroquinolones can be used to treat anaerobes?

Answer 5

-pradofloxacin
-moxifloxacin
-gatifloxacin

Question 6

Which antimicrobials can be used to treat Pseudomonas?

Answer 6

-piperacillin
-ceftazidime
-aminoglycosides
-fluoroquinolones
-possibly carbapenems and ‘amphenicols

Question 7

Which antimicrobials can be used to treat Staphylococcus?

Answer 7

-antistaphylococcal penicillins
-possibly cephalosporins, macrolides, FQs, TMS

Question 8

Which gram pos. aerobes have we discussed?

Answer 8

-Streptococcus
-Enterococcus

Question 9

Which gram pos. facultative anaerobe have we discussed?

Answer 9

Staphylococcus (MRSA and MRSP)

Question 10

Which gram neg. FAs have we discussed?

Answer 10

-Pasterurellaceae family
-Enterobacteriaeceae family

Question 11

Which gram neg. anaerobe have we discussed?

Answer 11

Bacteroides fragilis

Question 12

Which gram neg. FA/ preferential gram neg. aerobe have we discussed?

Answer 12

Pseudomonas aeruginosa