Lecture 13 Flashcards
targeting sequences in mitochondrial proteins
matrix, inner membrane with STAs, inter-membrane space targeting sequence (gets cleaved), outermsmbrane with STA
anterograde
forward - ER to cis-golgi
retrograde
reverse - cis-golgi to ER
COPII
anterograde, Sar1
COPI
retrograde, ARF
v-SNARES
SNARES on vesicles
t-SNARES
target cell SNARES
what does the docking in in vesicle formation
SNARES
CREB
transcription factor, when activated, forms a transcription activation complex
Process of signal transduction for CREB
signal-GCPR = activate G-protein (alpha) = activates effector = make cAMP to bind to PKA = phosphorylates CREB
formation of clathrin
sorting signal of a receptor binds to AP complex which triggers association of clathrin
components of LDL
has a ApoB protein that the receptor arm binds to