Lecture 12- Protein Delivery Using Vesicles

Question 1

Structure of golgi apparatus

Answer 1

Have folds called cisterna

Have cis face- “receiving” side

Have trans face- “shipping” side

Question 2

Function of golgi apparatus

Answer 2

Modify and distribute proteins and membrane lipids made in ER

Question 3

Constitutive exocytosis

Answer 3

Release mucus in small intestine

Cell growth- cells must increase surface area prior to cytokinesis

Question 4

Regulated exocytosis

Answer 4

Export of insulin proteins

Question 5

Lysosome

Answer 5

Large vesicle that contains hydrolysis enzymes to digest things and transport proteins to remove things from inside the lysosome to the cytosol

Question 6

M6P signal

Answer 6

Binds to future lysosome enzyme

Question 7

M6P receptor Affinity for cargo

Answer 7

High in Golgi (ph 6.5)
Low in lysosome (pH < 6.0)

Question 8

Endosome

Answer 8

Immature lysosome