Lecture 11- Vesicles Flashcards
What is the function of a vesicle?
Move material within endomembrane system
How do vesicles form?
Cargo molecules (ligands) stick to cargo receptors
Folding a membrane into a ball using a coat protein to make a coated vesicle
Clathrin
A type of coat protein
It binds to a flat phopholipid bilayer and bends it into a ball shape to make a vesicle.
What connects Clathrin to Cargo receptor?
Adaptin
What closes the vesicle?
Dynamin
How does uncoating occur?
A. Adaptin-GTP -> Adaptin-GDP
B. Adaptin-GDP -> Adaptin-GTP
A. Adaptin-GTP -> Adaptin-GDP
(Active form to inactive form)
Iron is transported into the blood using iron transporting proteins called __
Transferrins- synthesized in liver cells
How do vesicles move?
It’s gonna be moved along microtubes
Microtubules
Have polarity and a characteristic arrangement in animal cells
Two types of motor prtoteins
Kinesin (+)
Dynein (-)
Exocytosis uses __; Endocytosis uses __
A. Dyneins… Kinesins
B. Dyneins…. Dyneins
C. Kinesins … Dyneins
D. Kinesis… Kinesins
C. Kinesins … Dyneins
ER -> Golgi uses ___
A. Dyneins
B. Kinesins
C. Both
A. Dyneins
SNAREs
Membrane proteins act like snakes (2 snakes)
Allow the vesicles to fuse with the proper target
Vesicles fuse with target membrane when SNAREs pull together
