Lecture 11B Flashcards

1
Q

Effective against either gram + or -

A

Narrow spectrum

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2
Q

Effective against both gram + and -

A

Broad spectrum

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3
Q

What is the job of Penicillin’s?

A

Inhibit cell wall synthesis

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4
Q

Is Penicillin’s bactericidal or bacteriostatic?

A

Bactericidal

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5
Q

Beta lactam Antibiotics include…

A

Penicillin and Cephalosporins

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6
Q

Beta lactamase is also known as

A

Bacterial enzymes

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7
Q

If a bacteria produces beta lactamase, what does it inhibit?

A

I reduces the effectiveness of certain antibiotics

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8
Q

Amoxicillin + Clavulanic acid makes…

A

Clavamox

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9
Q

True or false: Clavulanic acid is a B-lactamase inhibitor

A

True

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10
Q

True or false: allergic reactions are most likely to occur in Penicillin’s

A

True

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11
Q

What animals should not recieve oral Penicillin because it causes diarrhea?

A

Horses, rabbits, or guinea pigs

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12
Q

What is the trade name for Amoxicillin?

A

Amoxi tab®️ or Amoxi drop®️

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13
Q

What is Amoxicillin used to treat?

A

Abscesses, UTI, and URI

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14
Q

Adverse reactions of Amoxicillin

A

GI upset and high doses can cause neurotoxicity

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15
Q

This is added to Procaine Penicillin to extend the dosing interval; 1 dose every 3 days

A

Benzathine

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16
Q

True or false: white liquids should never be given SQ

A

False; they should never go IV

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17
Q

These antibiotics are Beata-lactam’s that disrupt the cell wall and are closely related to Penicillin’s

A

Cephalosporins

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18
Q

Are Cephalosporins bactericidal or bacteriostatic?

A

Bactericidal

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19
Q

True or false: 4th generation Cephalosporins are more gram + that 1st generation

A

False; they are more gram -

20
Q

What is the generic name for Rilexine®️?

A

Cephalexin

21
Q

What is the trade name for Ceftiofur?

A

Naxcel®️

22
Q

What is the trade name for Cefovecin?

A

Convenia®️

23
Q

How many doeses of Cefovecin should be given?

A

1 dose the last 2 weeks

23
Q

What species is Cefovecin good for?

A

It is great for cats

24
Are Tetracyclines bactericidal or bacteriostatic?
Bacteriostatic
25
Tetracyclines are used to treat...
Tick borne diseases and to control tear staining
26
What are the adverse reactions of Tetracyclines?
Yellow to brown staining of the tooth enamel, fever hairloss and depression in cats, hepatic/renal toxicity
27
Why should Tetracyclines not be given with milk products?
I decreases absorption
28
What is the trade name for Doxycycline?
Doxirobe®️ or Virbramycin®️
29
Doxycycline is used to treat
Lyme disease, inflammation, and skin infections
30
This drug is not approved for use in horses because it can alter the GI flora. If given too rapidly, they could die
Doxycycline
31
Are Aminoglycosides bactericidal or bacteriostatic?
Bactericidal
32
True or false: Aminoglycosides should never be given orally because it has poor absorption
True
33
Gentamicin, Amikacin, and Neomycin are all...
Aminoglycosides
34
What is the trade name for Gentamicin?
Gentocin®️
35
What is the trade name for Amikacin?
Amiglyde V®️
36
What can Amikacin cause in cats?
Deafness
37
True or false: Neomycin should not be used as an injectable
True
38
True or false: Gentamicin can be used extra label
False; it should not be used extra label per AVMA
39
Why should Gentamicin not be used in rabbits
It causes nephrotoxicity
40
What are the adverse reactions of Gentamicin?
Ototoxicity, nephrotoxicity, and acute renal disease withing 1 week
41
Contraindication for Gentamicin
Should not be used in renal insufficiency or severely dehydrated patients
42
Is Fluoroquinolones bactericidal or bacteriostatic?
Bactericidal
43
This antibiotic is safe for use in rabbits
Fluoroquinolones
44
Adverse reactions of Fluoroquinolones
Alterations in cartilage growth/production- do not use in large breed dogs less than 18 months and small breed dogs less than 8 months, retinal detachment in cats with high doses, seizures, V/D
45
Examples of Fluoroquinolones
Baytril®️(enrofloxacin), Orbax®️(Orbifloxacin), Zeniquin®️(Marbofloxacin)