lecture 11 + ch6+11(some) Flashcards
what % of ppl aged 65+ in Canada have a psychological disorder? also, who specifically in this age group has higher rates?
20%
people living in health care and social institutions
__% of older adults report mental health problems get treatment
50%
cognitive declines and other changes occuring with age
cognitive declines:
- perceptual speed
- episodic memory
- spatial visualization
- reasoning
changes in structure and functioning in areas associated w executive control (hippocampus, PFC)
older adults recruit more brain regions than do younger adults, so may need additional executive resources to perform the same task
delirium
acute state of confusion
disoriented and impaired attentional skills and consciousness
onset is abrupt with a short duration, and symptoms may fluctuate throughout the day
what % of those in urgent care facilities (esp intensive care) experience delirium?
10-30%
delirium causes
- fever, malnutrition, severe dehydration, acute infection
- meds and subtances
- brain trauma/injury
- brain changes due to neurocognitive disorder
- environmental stressors
delirium treatment
first step is identifying underlying cause
rapid treatment= better longterm outcome
acute delirium (triggered by substance withdrawal) treated with antipsychotics
psychosocial treatment is used to help ppl cope with anxiety and hallucinations
major neurocognitive disorder
previously called dementia
gradual deterioration of brain functioning that impacts judgement, memory, language and other processes that interfere w independence
mild neurocognitive disorder
new to dsm5
focus on early stages of cognitive decline
modest decline that does not interfere with independence yet
causes of major/mild neurocognitive disorders
alzheimers
vascular disease
traumatic brain injury
parkinsons
substance abuse
huntingtons disease
prion disease
neurocognitive disorder due to alzheimers disease symptoms
initial memory + learning issues that develop gradually and slowly get worse
irritable and social withdrawal
aphasia (cant think of words they wanna say), apraxia (loss of fine motor skills, ex; gestures) , and anomia (cant recognize and name objects u used to known/name)
difficulty planning, organizing, sequencing or abstracting info
what is the most prevalent neurodegenerative disorder
neurocognitive disorder due to alzheimers disease
causes of neurocognitive disorder due to alzheimers disease symptoms
there is widespread synaptic and neuronal loss
specifically, there are 2 specific structural abnormalities that affect this:
- neurofibrillary tangles: Tau fibres twist
- neuritic (beta amyloid) plaques: plaque made of beta amyloid that aggregates in spaces between neurons
these 2 things can be caused by gene mutations in genes that code for proteins that typically clear beta amyloids from the brain. obvi when this gene is mutated, it won’t do this action properly (resulting in the plaque). can also be caused by environmental factors like smoking!
can gene mutations be inherited?
yes
what are Tau fibres?
proteins that help transport nutrients in the nerve cell
neurocognitive disorder due to vascular disease
cognitive decline due to reduced blood flow to brain
this can be a one time event (stroke) or ongoing
cognitive issues have abrupt onset, like sudden numbness in face/arm/leg, confusion or trouble speaking, trouble seeing, etc
what is the 2nd most frequent cause of neurocognitive disorders after alzheimers disease?
vascular disease
causes of neurocog. disorder due to vascular disease
atherosclerosis, which is thickening or arteries due to plaque build up. the arteries narrow and blood flow is reduced.
neurocognitive disorder due to traumatic brain injury cause+ symptom
results from hit to the head
ranges from mild to severe
symptoms + duration range depending on what brain area affected
(concussion= not too serious, cerebral contusion= bruised brain, cerebral laceration= brain is pierced, chronic traumatic encephalopathy= repeated concussions over time)
neurocognitive disorder due to parkinsons disease symptoms + cause
4 main symptoms
1. tremor of hands/arms/legs/jaw/face
2. rigidity of limbs and trunk
3. slowness in initiating movement
4. drooping posture or impaired balance and coordination
occurs due to damage to neurons in substantia nigra
- dopamine loss
- dopamine neurons are dying due to accumulation of Lewy bodies (plaque build up INSIDE of neuron)
substance induced neurocognitive disorder
delirium associated w substance intoxication, withdrawal, use of multiple substances, or inhalants
symptoms of this are common in those w history of heavy substance use
exposure to environment toxins can also cause this
neurocognitive disorder due to huntingtons disease (causes, symptoms, treatment)
rare, genetically transmitted, degenerative disorder
(kids have 50% chance of getting this from a parent who has it)
symptoms: cognitive, emotional, and physical disturbances
no treatment + death usually happens 15-20 years after it starts.
neurocognitive disorder due to prion disease (cause)
Prions make spongy holes in the brain, which give it a sponge-like texture and causes neurocognitive symptoms
ex; mad cow disease