Lecture 11 Flashcards
What are the 5 different subgroups of vaccines?
inactivated attenuated subunit toxoid conjugate
what is a conjugate vaccine?
allows T cell help for polysaccharide conjugated to a protein
something with low antigenic property bound to something with a high antigenic property
can alter the immune response to get TH cells involved and switch to a T dependent immune response
what is an adjuvant?
a substance administered with an antigen to promote the immune response
what are examples of the next generation of vaccines?
mRNA vaccines
viral vector vaccines
DNA vaccines
VLP
what types of vaccine are Moderna and the PFzier vaccine?
mRNA vaccines
different temperature regulation and delivery mechanisms
what are some of the challenges with these vaccines?
producing storing how immunogenic time for trial data availability globally