Lecture 11 Flashcards
True or false: dendrites are the principle synaptic input sites
True
How do signals or voltage changes Flow
Signals flow from dendrites to soma to axons and finally to synapses and penises
Where is information primarily received in a neuron
Information is received primarily by the dendrites and soma but synaptic input can also be found and axons and axon terminal
Where is information integrated?
Neuronal soma
Where is the decision made for whether an action potential will fire?
The decision is made at the Axon hillock
How does the information received translate into finding patterns?
Firing patterns are dependent on ion channels expressed in the axon
True or false? Axons act as transmitter’s of information to the axon terminal
True
Where does the conversion of an action potential into chemical signal occur?
It occurs in the axon terminal
What type of channels are found at the synaptic sites?
Ligand gated channels
Where in a neuron are synaptic sites found?
Predominately in the dendrites and the somatic but can also be found in axons
Where are Sodium and delayed rectifying potassium channels located
In parts of the neuron that display action potential’s
How does a neuron with only fast sodium currents and delayed rectifying potassium current respond to continuous depolarization
And neuron will exhibit repetitive spiking and the rate of firing could be regulated by the presence of an a type potassium current
How does the neuron with a slowly accumulating potassium current such as the calcium activated potassium spikes underlying the SAHP respond to continuous depolarization?
This neuron will display spike frequency adaptation
True or false? Neurons can also exhibit rhythmic bursting behaviour by exploiting the interplay between depolarizing and hyperpolarizing friends
True
What are regenerative signals
Action potential’s all or nothing
What are non-regenerative signals?
Sub threshold potential’s or graded potential’s that spread for short distances along Cell membranes
How are receptor potentials generated
They are generated during the transduction of sensory stimuli
How are post synaptic synaptic potential is generated
They are generated by the opening of an agonist activated channel
What does the spread of electrical current depend on
Cell geometry, electrical resistance of aqueous solutions, cell membrane and membrane capacitance
True or false? Passive responses decay with distance through an axon but active responses do not
True
What are PSP
Post synaptic potential’s
What are post synaptic potential is also referred to
Graded potential’s or GP
What is a characteristic of an excitatory postsynaptic potential or EPSP
Depolarization
What is a characteristic of an inhibitory postsynaptic potential or I PSP
Hyperpolarization
