Lecture 11 Flashcards
Chemical Agents in Periodontal Care
systemic delivery
the chemical agent is circulated systemically throughout the body
topical delivery
intraoral placement of topical chemical agents/controlled-release devices
criteria for effective chemical agents
must reach the site of the disease activity
efficacy: ability to inhibit oral bacterial growth and be delivered in bacteriostatic/bactericidal concentrations
substantivity: remain in place long enough to be effective
therapeutic mouthrinses
many contain chemical ingredients that have little or no effect against gingivitis
clinical studies support the effectiveness of therapeutic mouthrinses used in addition to
proper home care
why not just mouthrinse
the surface of dental plaque biofilm is covered by the extracellular protective matrix/protective barrier
mechanical biofilm control is a must in order to disrupt the structure of the biofilm and allow the chemical agents to reach the bacteria themselves
therapeutic mouthrinses uses
can provide therapeutic benefit: decrease biofilm to decrease gingivitis, decrease risk of dental caries, aid in dentinal hypersensitivity
two mouthrinse ingredients that have demonstrated effectiveness against gingivitis are
chlorhexidine gluconate
essential oils
chlorhexidine gluconate
most effective
available by prescription
rinse twice daily
bactericidal
displays substantivity (binds to tissue, slowly released)
what is the most effective antimicrobial agent for long term reduction of biofilm and gingivitis
chlorhexidine
cons of chlorhexidine
may cause discoloration of the tongue, taste alteration, increased extrinsic stain, increase in calculus formation, prescription, costly
patients who benefit from chlorhexidine gluconate
special needs patients
postsurgical care patients
candida infections
high caries risk
oral piercings/implants
preprocedural rinse for powered instrumentation
essential oils
also control biofilm: antibiofilm/antigingivitis
over the counter
less expensive
lack the side effects
4 essential oils
thymol, menthol, eucalyptol, methyl salicylate
controlled-release antimicrobial agents
consists of an antibacterial chemical embedded in a carrier material
placed directly into the perio pocket, dissolving slowly providing a steady release of the antimicrobial agent
most subject subgingival bacteria to therapeutic levels of antimicrobial agents for approx. 1 week
non-responsive pockets/sites