Lecture 10: Substance Abuse and Addictive Disorders Flashcards
drug
any substance other than food affecting the body or mind, including alcohol, tobacco, and caffeine
substance intoxication
cluster of changes in behavior, emotions, or thought caused by substances
substance use disorder
maladaptive behaviour patterns and reactions caused by repeated substance use
diagnosis of substance use disorder
diagnosis requires the presence of at least two of the following symptoms within a 1-year period:
- substance is often taken in large amounts or over a longer period than intended
- unsuccessful efforts or persistent desire to reduce or control substance use
- much time spent trying to obtain, use, or recover from the effects or substance use
- failure to fulfill major role obligations at work, school, or home as a result of repeated substance use
- cessation or reduction of important social, occupational, or recreational activity because of substance use
- continued use of substance despite persistent social or interpersonal problems caused by it
- continued use in dangerous situations
- continued to use substance despite awareness that it’s causing or worsening physical or psychological problem
- craving for substance
- tolerance effects
- withdrawal effects
tolerance
need for increasing doses of substance to produce desired effect
withdrawal
unpleasant and sometimes dangerous symptoms occurring with drug stopping or cutting back
depressants
drugs that slow activity of the CNS, by reducing tensions and inhibitions and may interfere with judgment, motor activity and concentration. include:
- alcohol
- sedative-hypnotic (anxiolytic) drugs
- opioids/narcotics
alcohol
a type of drug in alcoholic beverages
- women typically become more intoxicated than men on equal doses of alcohol
- 0.09% of alcohol in the blood is the threshold for intoxication. 0.55% is likely fatal
- the effects of alcohol subside when concentration is lowered: alcohol is broken down by the liver into carbon dioxide and water, and expelled
binge drinking episode
five or more drinks on a single occasion
alcohol use disorder/alcoholism
characterized by regular intake of large amounts of alcohol, which eventually interfered with daily life
delirium tremens (DTs)
extreme withdrawal reaction that includes visual hallucinations and clouded mind
korsakoff’s syndrome
vitamin B deficiency due to long-term excessive alcohol use, marked by memory loss and other problems with nervous system
fetal alcohol syndrome
abnormalities in the fetus due to alcohol use by the pregnant mother, characterized by face deformities, intellectual disability, heart defects, slow growth and hyperactivity
cirrhosis
irreversibly scarred and dysfunctional liver, can be caused by excessive drinking
social impacts of alcoholism
play a role in suicides, assaults, rapes, and accidents. can destroy families, social relationships, and careers
college binge drinking
has impacts on mood, memory, and brain/heart functioning and is related to academic problems and dropping out of college
sedative-hypnotic (anxiolytic) drugs
produce feelings of relaxation and drowsiness. 2 types:
- low doses: calming or sedative effect
- high doses: sleep inducers or hypnotics
barbiturates
addictive and dangerous drugs, which were prescribed by some physicinas in the first half of the 20th century
benzodiazepines
anti-anxiety drugs that are not commonly prescribed by physicians, increase GABA activity
opioids/narcotics
all drugs derived from opium, such as morphine and heroine. cause CNS depression: pleasurable and calming feelings, nausea, narrowing of the pupils, and constipation. can be smoked, inhaled, snorted, injected, or swallowed.
endorphines
opioids attach to receptors that normally receive endorphins, which are neurotransmitters that help relieve pain and reduce emotional tension
use of opium
- in the past, opium was used as a painkiller, but it is very addictive. later, opium was converted into morphine.
- morphine was used because it is stronger than opium, but it also turned out to be addictive
- from morphine, another painkiller can be made: heroin. this was used for several years as a cough medicine and for other medical purposes, however it was discovered that heroin is even more addictive than morphine
opioid use disorder
excessive use of opioids, which interferes with daily functioning
dangers of opioid use
overdose, ignorance to tolerance, getting impure drugs, and infection from dirty needles
stimulants
substances that increase activity in the CNS, resulting in increased blood pressure, heart rate, alertness, and rapid behavior and thinking
cocaine (stimulant)
central active ingredient coca plant, most powerful stimulant, increases dopamine, norepinephrine, and serotonin activity, which overstimulates the nervous system, resulting in a euphoric, wakeful, and aroused state. snorted and sometimes injected or smoked
cocaine intoxication
when high doses are taken, symptoms include poor muscle coordination, aggression, anger, grandiosity, compulsive behavior, confusion, anxiety, and bad judgement
cocaine-induced psychosis
when high doses are taken, experiencing delusions and hallucinations