Lecture 10 Flashcards
Loose CT is made of what?
Collagen and Elastic
Dense are made of what?
Collagen
what are 4 features of Loose CT?
More Cells than collagen
Type I collagen
Found beneath epithelial tissues (tunica adventitia)
Has fibroblasts, mast cells, macrophages, and capillaries
4 features of Dense Regular?
More Collagen than cells
Thicker bundles of collagen
Highly ordered
Found in tendons/ligaments
4 features of Dense Irregular?
High Ratio of Fibrous components to Fibroblasts
Thick bundles of collagen
No specific orientation of collagen
Found in fascia, submucosa of GI tract, Dermis of Integument
What is Embryonic tissue called in the umbilical cored?
Wharton’s jelly
Where does white fat come from and what is needed?
Mesenchymal stem cells and C/EBPs are needed.
What is needed to make Brown fat?
MYF5 + PAX7
BMP7 & PRDM16
4 features of Ehlers-Danols Syndrome
Inherited CT disorder
Defect in collagen
Collagen has reduced tensile strength
Skin can stretch/joints hyper mobile
4 features of Marfan Syndrome
Elastic tissue is weakened
Ocular= Myopia, detached lens
Skeletal= long/thin arms, hollow chest, scoliosis, elongated fingers
Cardiovascular=prolapse of mitral valve
What is the ultimate cause of Marfan syndrome?
Defect in Fibrillin-1, leads to increase proteoglycans
What are the 4 types of GAGs?
Hyaluronic Acid
Heparin/Heparin Sulfate
Chondroitin Sulfate/Dermatan
Keratan
