Lecture 10 Flashcards
Digestion converts ingested materials into
molecules small enough for absorption
Absorption occurs through
Active transport, simple diffusion, facilitated diffusion, secondary active transport, & endocytosis
Monomers of carbohydrates, proteins, and nucleic acids are absorbed via
blood capillaries
Monomers of lipids are absorbed through
lacteals (lymphatic systems)
uptake of glucose or galactose
SGLT1 is the Na+-coupled transporter that mediates the uptake of glucose or galactose from the lumen of the small intestine into the enterocyte.
fructose diffusion
GLUT5 mediates the facilitated diffusion of fructose into the enterocyte.
Enterocyte
= Villie –> brush border –> enterocyte
Once the monosaccharides are inside the enterocyte,
GLUT2 mediates their efflux across the basolateral membrane into the interstitial space.
The 3 monosaccharides (i) glucose, (ii) galactose, & (iii) fructose, are absorbed by the small intestine in a 2-step process
[uptake across the apical membrane into the epithelial cell], &
[coordinated exit across the basolateral membrane]
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