Lecture 1 and 2 quiz Flashcards

1
Q

Which of the following terms describes the protein shell that surrounds the viral genome?

capsomere

virion

capsid

envelope

matrix

A

capsid

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2
Q

Viruses play a major role in the ecology of the ocean by doing which of the following?

By lysing unicellular organisms and releasing carbon and oxygen back into the ocean.

By infecting photosynthetic bacteria and increasing their growth.

All of the above statements are correct.

By killing off fish and preventing them from becoming too plentiful.

By infecting harmful bacteria found in the ocean and limiting their growth.

A

By lysing unicellular organisms and releasing carbon and oxygen back into the ocean.

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3
Q

If you wanted to show that an infectious agent is a virus, what experiment could you do?

Show that the agent can pass through a porcelain filter and is still infectious.

Show that agent contains a lipid membrane.

Show that the agent can be seen under a light microscope.

Show that the agent can be diluted and can still cause disease in an animal.

Show that the agent can form single colonies on an agar plate.

A

Show that the agent can pass through a porcelain filter and is still infectious.

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4
Q

What does the word “virus” mean in Latin?
death

liquid

infectious agent

disease

poison

A

poison

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5
Q

The word “phage” is a shortened version of the name of a virus that can infect which type of organism?
human cell

insect cell

bacterial cell

plant cell

eukaryotic cell

A

bacterial cell

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6
Q

Which of the following processes in cells was NOT discovered by studying a virus?

DNA replication in both prokaryotic and eukaryotic cells

regulation of gene expression in eukaryotic cells.

the sequence of the genetic code.

mRNA splicing in eukaryotic cells

DNA is the genetic material

A

the sequence of the genetic code.

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7
Q

The lipid membrane that surrounds the nucleocapsid of some virus particles is called the:

matrix

tegument

envelope

glycoprotein

capsid

A

envelope

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8
Q

The nucleocapsid describes the structure that includes the:

envelope and the glycoproteins

capsid and the genome

helical capsid and an envelope

capsid and the envelope

icosahedral capsid and an envelope

A

capsid and the genome

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9
Q

Depending on the type of virus, which of the following is a function of the virus capsid?

To ensure delivery of the genome into the host cell.

To protect the viral genome from nucleases.

To protect the viral genome from damage by UV light.

All of the above functions are correct.

To attach to the correct type of host cell.

A

All of the above functions are correct.

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10
Q

Most viruses that use a spherical shaped capsid arrange their capsid proteins with which of the following symmetries?

dodecagon

tetrahedral

cubic

helical

icosahedral

A

icosahedral

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11
Q

Which of the following is NOT a characteristic of a regular icosahedron?

It has 20 sides with 3-fold symmetry.

It has 12 vertices of 5-fold symmetry.

It has 20 triangular faces.

It has 6 square faces.

It has 30 edges with 2-fold symmetry

A

It has 6 square faces.

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12
Q

How many copies of the capsid protein would there be in an icosahedral capsid with a Triangulation number of 7?

A

420

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13
Q

Which of the following h and k values will produce a triangulation number of 13?

1 and 3

2 and 4

2 and 3

1 and 2

1 and 1

A

1 and 3

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14
Q

Which of the following describes the number of subunits per turn in a helical capsid?

m (mu)

r (rho)

Triangulation number

P (pitch)

symmetry

A

m (mu)

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15
Q

What does the term “quasi-equivalent” mean with respect to the proteins in an icosahedral capsid?

There can be more than one type of glycoprotein in the envelope.

All of the proteins interact in a 5-fold arrangement.

They all use the “jelly-roll” protein structure.

There are different proteins in the capsid with similiar shapes.

If the identical protein is used, it has both 5-fold and 6-fold interactions with the other proteins in the capsid.

A

If the identical protein is used, it has both 5-fold and 6-fold interactions with the other proteins in the capsid.

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16
Q

It is possible to get high resolution images of enveloped virus particles using x-ray diffraction.

True

False

A

False

17
Q

Cryoelectron microscopy uses computer reconstruction of images of multiple virions to produce a high resolution image of a virion or capsid.

True

False

A

True

18
Q

Viral envelopes often have very different lipid compositions than the cellular membranes that they originate from.

True

False

A

false

19
Q

How many subunits would each face of a T=7 virus particle contain?

30

9

21

18

12

A

20

20
Q

How many hexamers would a T=16 virus particle contain?

180

150

70

220

90

A

150