Lecture 1

Question 1

Time to double knowledge

Answer 1

12 hours

Question 2

What is evidence based med and what is it not?

Answer 2

It is mathematical, high quality research, and large sample sizes. This helps inform clinical decision making, set protocol/standards and determine reimbursement.

It is not replacement of judgment, all inclusive or diminish other treatment methods.

Question 3

Scientific Method

Answer 3

Empirical observation 
Form hypothesis 
Experiment 
Modify hypothesis
Retest 
Communicate results

Question 4

4 alternatives to EBM

Answer 4

1. Anecdotal: narrative based with low evidence.
2. Press cutting: Emphasizes results
3. Consensus: Protocol based on consensus
4. Cost minimization: Goal to care for pt but limit costs.

Question 5

Anecdotal. What is it and what are some examples?

Answer 5

Narrative based.
Low level of evidence. N=1
Useful for some- not all.
EX: Harold Ridley observing effects of PMMA in eyes vs glass. Better outcome= first IOL and new CL material.
Ex: Latisse used to treat hypotrichosis
Ex: Intense pulsed light used for rosacea

Question 6

Press cutting. What is it? what is a disadvantage?

Answer 6

Emphasizes results without considering validity of study or methods. Disadvantage: Junk science. May omit risks.

Question 7

Consensus. What is it, what are examples, and what is a disadvantage?

Answer 7

Protocol based on consensus. Less common today.
GOBSAT, Delphi, TFOS.
Disadvantage: no objective. Influenced by sponsor.

Question 8

Cost minimization

Answer 8

Challenges: limited resources that are lower cost.