lecture 1

Question 1

Infectious Causes of ^RBC destruction

BAM llama

obvious…

Answer 1

1. RBC parasites (babesia, anaplasma marginale, mycoplasma hemollama)
2. leptospirosis
3. equine infectious anemia (EIA)

Question 2

what is the major cause of dec RBC production

Answer 2

chronic infectious/inflame dz

Question 3

what is a wbc parasite

Answer 3

anaplasma phagocytophila

Question 4

what does coggins test test for?

Answer 4

EIA (equine infectious anemia)

Question 5

what are alloantigens?

Answer 5

antigens that induce an immune response within the same species

(blood types)

(antibodies produced against alloantigens = alloantibodies)

Question 6

how many blood groups

horses

cows

Answer 6

(think 7-11)

7

11

Question 7

what horse blood is most antigenic?

which breeds most likely negative?

which are most likley positive?

Answer 7

Aa/Qa

quarter, standard, morgan (drafts, shetlands)

thoroughbreds, arabians

Question 8

1. what is a major cross match?
2. a minor?

Answer 8

1. donor RCBs + recipient serum

Checks for patient alloantibodies against donor RBCs

2. recipient RBCs + donor serum

Checks for donor allonantibodies against patient RBCs

Question 9

1. What drugs do you give if severe rxn to transfusion?
2. what if mild or prepping for transfusion?

Answer 9

1. corticosteroids, epinephrine
2. flunixin meglumide (NSAID)

tripleanamine, diphenhydramine (antihistamine)

Question 10

How do you check for transfusion efficiency? (4 things)

is PCV good indicator?

Answer 10

rapid decline in HR, decline in blood lactate, decline in RR, ^ in PvO2

no